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Thyroid cancers and cases of melanomas, colorectal, endometrial, ovarian and liver cancers showed moderate nucleolar and membranous positivity. Remaining cancers were weakly stained or negative.
GENE INFORMATION
Gene name
SNU13 (HGNC Symbol)
Synonyms
15.5K, FA-1, NHP2L1, SNRNP15-5, SPAG12, SSFA1
Description
SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5) (HGNC Symbol)
Entrez gene summary
Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]