Expression of SLC25A17 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17

Protein class

Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Carcinoid

STAINING SUMMARY

HPA052708

GENE INFORMATION
Gene name	SLC25A17 (HGNC Symbol)
Synonyms	PMP34
Description	Solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 (HGNC Symbol)
Entrez gene summary	This gene encodes a peroxisomal membrane protein that belongs to the family of mitochondrial solute carriers. It is expressed in the liver, and is likely involved in transport. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Chromosome	22
Cytoband	q13.2
Chromosome location (bp)	40769630 - 40819399
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100372 (version 83.38)
Entrez gene	10478
UniProt	O43808 (UniProt - Evidence at protein level)
neXtProt	NX_O43808
Antibodypedia	SLC25A17 antibodies

PROTEIN BROWSER

SLC25A17-001	SLC25A17-004	SLC25A17-010	SLC25A17-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC25A17-001 ENSP00000390722 ENST00000435456	O43808 [Direct mapping] Peroxisomal membrane protein PMP34 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001561 [fatty acid alpha-oxidation] GO:0005347 [ATP transmembrane transporter activity] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005777 [peroxisome] GO:0005778 [peroxisomal membrane] GO:0005779 [integral component of peroxisomal membrane] GO:0006635 [fatty acid beta-oxidation] GO:0015217 [ADP transmembrane transporter activity] GO:0015228 [coenzyme A transmembrane transporter activity] GO:0015230 [FAD transmembrane transporter activity] GO:0015866 [ADP transport] GO:0015867 [ATP transport] GO:0015908 [fatty acid transport] GO:0016020 [membrane] GO:0035349 [coenzyme A transmembrane transport] GO:0035350 [FAD transmembrane transport] GO:0043132 [NAD transport] GO:0043231 [intracellular membrane-bounded organelle] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0044610 [FMN transmembrane transporter activity] GO:0051087 [chaperone binding] GO:0051724 [NAD transporter activity] GO:0080121 [AMP transport] GO:0080122 [AMP transmembrane transporter activity] GO:1901679 [nucleotide transmembrane transport] Show all	307 aa 34.6 kDa	No	6
SLC25A17-004 ENSP00000385303 ENST00000402844	B0QYW5 [Direct mapping] Peroxisomal membrane protein PMP34 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005743 [mitochondrial inner membrane] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] Show all	225 aa 25.7 kDa	No	4
SLC25A17-010 ENSP00000404200 ENST00000434185	B1AHN4 [Direct mapping] Peroxisomal membrane protein PMP34 Show all	Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0016021 [integral component of membrane] GO:0043231 [intracellular membrane-bounded organelle] Show all	92 aa 10.5 kDa	No	0
SLC25A17-201 ENSP00000438355 ENST00000544408	F6RTR7 [Direct mapping] Peroxisomal membrane protein PMP34 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0016021 [integral component of membrane] Show all	234 aa 26.3 kDa	No	4