Q16665 [Direct mapping]
Hypoxia-inducible factor 1-alpha
D0VY79 [Target identity:100%; Query identity:100%]
Hypoxia-inducible factor 1, alpha subunit (Basic helix-loop-helix transcription factor), isoform CRA_b; Hypoxia-inducible factor 1, alpha subunit, variant K12NR

GO:0000989 [transcription factor activity, transcription factor binding]
GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding]
GO:0001666 [response to hypoxia]
GO:0001837 [epithelial to mesenchymal transition]
GO:0001938 [positive regulation of endothelial cell proliferation]
GO:0002248 [connective tissue replacement involved in inflammatory response wound healing]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003705 [transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007219 [Notch signaling pathway]
GO:0008134 [transcription factor binding]
GO:0010468 [regulation of gene expression]
GO:0010573 [vascular endothelial growth factor production]
GO:0010575 [positive regulation of vascular endothelial growth factor production]
GO:0010634 [positive regulation of epithelial cell migration]
GO:0010870 [positive regulation of receptor biosynthetic process]
GO:0016607 [nuclear speck]
GO:0019896 [axon transport of mitochondrion]
GO:0019899 [enzyme binding]
GO:0019901 [protein kinase binding]
GO:0030949 [positive regulation of vascular endothelial growth factor receptor signaling pathway]
GO:0031625 [ubiquitin protein ligase binding]
GO:0032364 [oxygen homeostasis]
GO:0032722 [positive regulation of chemokine production]
GO:0032909 [regulation of transforming growth factor beta2 production]
GO:0032963 [collagen metabolic process]
GO:0035035 [histone acetyltransferase binding]
GO:0035257 [nuclear hormone receptor binding]
GO:0042789 [mRNA transcription from RNA polymerase II promoter]
GO:0043565 [sequence-specific DNA binding]
GO:0043619 [regulation of transcription from RNA polymerase II promoter in response to oxidative stress]
GO:0045648 [positive regulation of erythrocyte differentiation]
GO:0045766 [positive regulation of angiogenesis]
GO:0045821 [positive regulation of glycolytic process]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046886 [positive regulation of hormone biosynthetic process]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0051000 [positive regulation of nitric-oxide synthase activity]
GO:0051541 [elastin metabolic process]
GO:0051879 [Hsp90 protein binding]
GO:0061418 [regulation of transcription from RNA polymerase II promoter in response to hypoxia]
GO:0061419 [positive regulation of transcription from RNA polymerase II promoter in response to hypoxia]
GO:0070101 [positive regulation of chemokine-mediated signaling pathway]
GO:0071347 [cellular response to interleukin-1]
GO:0071456 [cellular response to hypoxia]
GO:0090575 [RNA polymerase II transcription factor complex]
GO:1902895 [positive regulation of pri-miRNA transcription from RNA polymerase II promoter]
GO:1903377 [negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway]

A8MYV6 [Direct mapping]
Hypoxia-inducible factor 1, alpha subunit (Basic helix-loop-helix transcription factor), isoform CRA_a; Hypoxia-inducible factor 1-alpha

GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]

Q16665 [Direct mapping]
Hypoxia-inducible factor 1-alpha

GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0000989 [transcription factor activity, transcription factor binding]
GO:0001076 [transcription factor activity, RNA polymerase II transcription factor binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding]
GO:0001525 [angiogenesis]
GO:0001568 [blood vessel development]
GO:0001666 [response to hypoxia]
GO:0001755 [neural crest cell migration]
GO:0001837 [epithelial to mesenchymal transition]
GO:0001892 [embryonic placenta development]
GO:0001922 [B-1 B cell homeostasis]
GO:0001938 [positive regulation of endothelial cell proliferation]
GO:0001944 [vasculature development]
GO:0001947 [heart looping]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0002248 [connective tissue replacement involved in inflammatory response wound healing]
GO:0003151 [outflow tract morphogenesis]
GO:0003208 [cardiac ventricle morphogenesis]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003705 [transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006089 [lactate metabolic process]
GO:0006110 [regulation of glycolytic process]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006879 [cellular iron ion homeostasis]
GO:0006953 [acute-phase response]
GO:0007165 [signal transduction]
GO:0007219 [Notch signaling pathway]
GO:0007595 [lactation]
GO:0008134 [transcription factor binding]
GO:0008284 [positive regulation of cell proliferation]
GO:0008542 [visual learning]
GO:0009612 [response to mechanical stimulus]
GO:0009651 [response to salt stress]
GO:0009749 [response to glucose]
GO:0010165 [response to X-ray]
GO:0010468 [regulation of gene expression]
GO:0010508 [positive regulation of autophagy]
GO:0010573 [vascular endothelial growth factor production]
GO:0010575 [positive regulation of vascular endothelial growth factor production]
GO:0010628 [positive regulation of gene expression]
GO:0010634 [positive regulation of epithelial cell migration]
GO:0010870 [positive regulation of receptor biosynthetic process]
GO:0010996 [response to auditory stimulus]
GO:0014074 [response to purine-containing compound]
GO:0014823 [response to activity]
GO:0014850 [response to muscle activity]
GO:0016607 [nuclear speck]
GO:0019896 [axon transport of mitochondrion]
GO:0019899 [enzyme binding]
GO:0019901 [protein kinase binding]
GO:0021502 [neural fold elevation formation]
GO:0021987 [cerebral cortex development]
GO:0030154 [cell differentiation]
GO:0030279 [negative regulation of ossification]
GO:0030502 [negative regulation of bone mineralization]
GO:0030949 [positive regulation of vascular endothelial growth factor receptor signaling pathway]
GO:0031514 [motile cilium]
GO:0031625 [ubiquitin protein ligase binding]
GO:0032007 [negative regulation of TOR signaling]
GO:0032025 [response to cobalt ion]
GO:0032355 [response to estradiol]
GO:0032364 [oxygen homeostasis]
GO:0032403 [protein complex binding]
GO:0032722 [positive regulation of chemokine production]
GO:0032869 [cellular response to insulin stimulus]
GO:0032909 [regulation of transforming growth factor beta2 production]
GO:0032963 [collagen metabolic process]
GO:0035035 [histone acetyltransferase binding]
GO:0035162 [embryonic hemopoiesis]
GO:0035257 [nuclear hormone receptor binding]
GO:0035690 [cellular response to drug]
GO:0035774 [positive regulation of insulin secretion involved in cellular response to glucose stimulus]
GO:0042127 [regulation of cell proliferation]
GO:0042493 [response to drug]
GO:0042541 [hemoglobin biosynthetic process]
GO:0042593 [glucose homeostasis]
GO:0042789 [mRNA transcription from RNA polymerase II promoter]
GO:0042826 [histone deacetylase binding]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043279 [response to alkaloid]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043565 [sequence-specific DNA binding]
GO:0043619 [regulation of transcription from RNA polymerase II promoter in response to oxidative stress]
GO:0043627 [response to estrogen]
GO:0045648 [positive regulation of erythrocyte differentiation]
GO:0045766 [positive regulation of angiogenesis]
GO:0045793 [positive regulation of cell size]
GO:0045821 [positive regulation of glycolytic process]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045906 [negative regulation of vasoconstriction]
GO:0045926 [negative regulation of growth]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046716 [muscle cell cellular homeostasis]
GO:0046886 [positive regulation of hormone biosynthetic process]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048514 [blood vessel morphogenesis]
GO:0048546 [digestive tract morphogenesis]
GO:0048661 [positive regulation of smooth muscle cell proliferation]
GO:0050790 [regulation of catalytic activity]
GO:0051000 [positive regulation of nitric-oxide synthase activity]
GO:0051216 [cartilage development]
GO:0051384 [response to glucocorticoid]
GO:0051541 [elastin metabolic process]
GO:0051879 [Hsp90 protein binding]
GO:0060135 [maternal process involved in female pregnancy]
GO:0060574 [intestinal epithelial cell maturation]
GO:0060992 [response to fungicide]
GO:0061030 [epithelial cell differentiation involved in mammary gland alveolus development]
GO:0061298 [retina vasculature development in camera-type eye]
GO:0061418 [regulation of transcription from RNA polymerase II promoter in response to hypoxia]
GO:0061419 [positive regulation of transcription from RNA polymerase II promoter in response to hypoxia]
GO:0070101 [positive regulation of chemokine-mediated signaling pathway]
GO:0070243 [regulation of thymocyte apoptotic process]
GO:0070244 [negative regulation of thymocyte apoptotic process]
GO:0070301 [cellular response to hydrogen peroxide]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071245 [cellular response to carbon monoxide]
GO:0071250 [cellular response to nitrite]
GO:0071257 [cellular response to electrical stimulus]
GO:0071260 [cellular response to mechanical stimulus]
GO:0071279 [cellular response to cobalt ion]
GO:0071333 [cellular response to glucose stimulus]
GO:0071347 [cellular response to interleukin-1]
GO:0071396 [cellular response to lipid]
GO:0071407 [cellular response to organic cyclic compound]
GO:0071456 [cellular response to hypoxia]
GO:0071482 [cellular response to light stimulus]
GO:0071542 [dopaminergic neuron differentiation]
GO:0072347 [response to anesthetic]
GO:0090575 [RNA polymerase II transcription factor complex]
GO:0097237 [cellular response to toxic substance]
GO:0097411 [hypoxia-inducible factor-1alpha signaling pathway]
GO:1900037 [regulation of cellular response to hypoxia]
GO:1902895 [positive regulation of pri-miRNA transcription from RNA polymerase II promoter]
GO:1903377 [negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway]
GO:1903599 [positive regulation of mitophagy]
GO:1903715 [regulation of aerobic respiration]
GO:1903928 [cellular response to cyanide]
GO:2000378 [negative regulation of reactive oxygen species metabolic process]
GO:2001054 [negative regulation of mesenchymal cell apoptotic process]