Expression of DCAF11 in cancer - Summary

CANCER ATLAS

Gene description

DDB1 and CUL4 associated factor 11

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA031157

GENE INFORMATION
Gene name	DCAF11 (HGNC Symbol)
Synonyms	GL014, PRO2389, WDR23
Description	DDB1 and CUL4 associated factor 11 (HGNC Symbol)
Entrez gene summary	This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2009]
Chromosome	14
Cytoband	q12
Chromosome location (bp)	24114195 - 24125242
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100897 (version 83.38)
Entrez gene	80344
UniProt	Q8TEB1 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TEB1
Antibodypedia	DCAF11 antibodies

PROTEIN BROWSER

DCAF11-001	DCAF11-002	DCAF11-003	DCAF11-005	DCAF11-010	DCAF11-018	DCAF11-019	DCAF11-020	DCAF11-021	DCAF11-022	DCAF11-023	DCAF11-024	DCAF11-025	DCAF11-027	DCAF11-028	DCAF11-030	DCAF11-031	DCAF11-033	DCAF11-034	DCAF11-035	DCAF11-036	DCAF11-038

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DCAF11-001 ENSP00000415556 ENST00000446197	Q8TEB1 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0016567 [protein ubiquitination] GO:0080008 [Cul4-RING E3 ubiquitin ligase complex] Show all	546 aa 61.7 kDa	No	0
DCAF11-002 ENSP00000380142 ENST00000396936	Q8TEB1 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0016567 [protein ubiquitination] GO:0080008 [Cul4-RING E3 ubiquitin ligase complex] Show all	446 aa 50.7 kDa	No	0
DCAF11-003 ENSP00000380146 ENST00000396941	Q8TEB1 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0016567 [protein ubiquitination] GO:0080008 [Cul4-RING E3 ubiquitin ligase complex] Show all	520 aa 58.8 kDa	No	0
DCAF11-005 ENSP00000452898 ENST00000559115	Q8TEB1 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0016567 [protein ubiquitination] GO:0080008 [Cul4-RING E3 ubiquitin ligase complex] Show all	546 aa 61.7 kDa	No	0
DCAF11-010 ENSP00000453115 ENST00000559144	H0YL98 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] Show all	265 aa 29.8 kDa	No	0
DCAF11-018 ENSP00000453132 ENST00000560901	H0YLB2 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		145 aa 16.1 kDa	No	0
DCAF11-019 ENSP00000453678 ENST00000561001	H0YMN6 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		128 aa 14.2 kDa	No	0
DCAF11-020 ENSP00000454139 ENST00000559288	H0YNT0 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Phobius predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		105 aa 11.8 kDa	No	0
DCAF11-021 ENSP00000453832 ENST00000559354	H0YN21 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		90 aa 9.9 kDa	No	0
DCAF11-022 ENSP00000453916 ENST00000561375	H0YN92 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		182 aa 20.5 kDa	No	0
DCAF11-023 ENSP00000453826 ENST00000560459	H0YN15 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Phobius predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		106 aa 11.8 kDa	No	0
DCAF11-024 ENSP00000453208 ENST00000560713	H0YLH4 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		116 aa 12.9 kDa	No	0
DCAF11-025 ENSP00000453587 ENST00000559382	H0YMF7 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		118 aa 13.1 kDa	No	0
DCAF11-027 ENSP00000454044 ENST00000558215	H0YNK2 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		73 aa 7.7 kDa	No	0
DCAF11-028 ENSP00000453470 ENST00000559017	H0YM56 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		108 aa 11.8 kDa	No	0
DCAF11-030 ENSP00000452915 ENST00000559593	H0YKR8 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		142 aa 15.7 kDa	No	0
DCAF11-031 ENSP00000453074 ENST00000557810	H0YL64 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		122 aa 13.3 kDa	No	0
DCAF11-033 ENSP00000453290 ENST00000559396	H0YLQ1 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		30 aa 2.9 kDa	No	0
DCAF11-034 ENSP00000453505 ENST00000558638	H0YM86 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		149 aa 16.6 kDa	No	0
DCAF11-035 ENSP00000453381 ENST00000559796	H0YLX7 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		67 aa 7 kDa	No	0
DCAF11-036 ENSP00000453805 ENST00000558408	H0YMZ4 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		93 aa 10.1 kDa	No	0
DCAF11-038 ENSP00000454129 ENST00000561041	H0YNS2 [Direct mapping] DDB1- and CUL4-associated factor 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		154 aa 17 kDa	No	0