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MYL9

CANCER ATLAS

Gene description

 Myosin, light chain 9, regulatory

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA039262
HPA045244
HPA059197

GENE INFORMATION

Gene name

 MYL9 (HGNC Symbol)

Synonyms

 LC20, MLC2, MRLC1, MYRL2

Description

 Myosin, light chain 9, regulatory (HGNC Symbol)

Entrez gene summary

 Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 20

Cytoband

 q11.23

Chromosome location (bp)

 36541484 - 36551447

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000101335 (version 83.38)

Entrez gene

 10398

UniProt

 P24844 (UniProt - Evidence at protein level)

neXtProt

 NX_P24844

Antibodypedia

 MYL9 antibodies

PROTEIN BROWSER
MYL9-001
MYL9-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MYL9-001
ENSP00000279022
ENST00000279022
P24844 [Direct mapping]
Myosin regulatory light polypeptide 9
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001725 [stress fiber]
GO:0005509 [calcium ion binding]
GO:0005829 [cytosol]
GO:0005859 [muscle myosin complex]
GO:0006936 [muscle contraction]
GO:0006937 [regulation of muscle contraction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007411 [axon guidance]
GO:0008307 [structural constituent of muscle]
GO:0016460 [myosin II complex]
GO:0030018 [Z disc]
GO:0032036 [myosin heavy chain binding]
GO:0048013 [ephrin receptor signaling pathway]
GO:0070527 [platelet aggregation]
Show all
 172 aa
19.8 kDa 		No 0
MYL9-002
ENSP00000217313
ENST00000346786
P24844 [Direct mapping]
Myosin regulatory light polypeptide 9
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005829 [cytosol]
GO:0005859 [muscle myosin complex]
GO:0006936 [muscle contraction]
GO:0006937 [regulation of muscle contraction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007411 [axon guidance]
GO:0008307 [structural constituent of muscle]
GO:0048013 [ephrin receptor signaling pathway]
GO:0070527 [platelet aggregation]
Show all
 118 aa
13.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.