Expression of MROH8 in cancer - Summary

CANCER ATLAS

Gene description

Maestro heat-like repeat family member 8

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA060298

GENE INFORMATION
Gene name	MROH8 (HGNC Symbol)
Synonyms	C20orf131, C20orf132, dJ621N11.3, dJ621N11.4
Description	Maestro heat-like repeat family member 8 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the maestro heat-like repeat family. The exact function of this gene is not known, however, in a genome-wide association study using hippocampal atrophy as a quantitative trait, this gene has been associated with Alzheimer's disease (PMID:19668339). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Chromosome	20
Cytoband	q11.23
Chromosome location (bp)	37101226 - 37179588
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000101353 (version 83.38)
Entrez gene	140699
UniProt	Q9H579 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9H579
Antibodypedia	MROH8 antibodies

PROTEIN BROWSER

MROH8-001	MROH8-002	MROH8-003	MROH8-004	MROH8-006	MROH8-007	MROH8-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MROH8-001 ENSP00000413544 ENST00000421643	Q9H579 [Direct mapping] Protein MROH8 Show all	Predicted intracellular proteins Show all	GO:0005488 [binding] Show all	600 aa 67.6 kDa	No	0
MROH8-002 ENSP00000389695 ENST00000434295	Q5JYR0 [Direct mapping] Protein MROH8 Show all	Predicted intracellular proteins Show all		34 aa 3.9 kDa	No	0
MROH8-003 ENSP00000339971 ENST00000343811	H0Y2W4 [Direct mapping] Protein MROH8 Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0005488 [binding] Show all	1069 aa 121.2 kDa	No	0
MROH8-004 ENSP00000400468 ENST00000422138	Q5JYQ9 [Direct mapping] Protein MROH8 Show all	Predicted intracellular proteins Show all		24 aa 2.8 kDa	No	0
MROH8-006 ENSP00000415930 ENST00000417458	H0Y7Y5 [Direct mapping] Protein MROH8 Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0005488 [binding] Show all	670 aa 76.7 kDa	No	0
MROH8-007 ENSP00000383290 ENST00000400440	H0Y3S5 [Direct mapping] Protein MROH8 Show all	Predicted intracellular proteins Show all	GO:0005488 [binding] Show all	629 aa 71 kDa	No	0
MROH8-201 ENSP00000383291 ENST00000400441	E7ETR9 [Direct mapping] Protein MROH8 Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0005488 [binding] Show all	946 aa 107.2 kDa	No	0