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Most malignant cells showed moderate to strong cytoplasmic immunoreactivity. Strongest staining was observed in cervical and urothelial cancers.
GENE INFORMATION
Gene name
VAPA (HGNC Symbol)
Synonyms
hVAP-33, VAP-A
Description
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]