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Gene name

Class

Subclass

Chromosome

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In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

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Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

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Score

Score

Antibodies

Column

 
 
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VAPA
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

VAPA

Gene description

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

Protein class

Plasma proteins
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Ubiquitous cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Approved based on 1 antibody.
HPA009174
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
N/A
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

VAPA (HGNC Symbol)

Synonyms

hVAP-33, VAP-A

Description

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

18

Cytoband

p11.22

Chromosome location (bp)

9914002 - 9960021

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101558 (version 83.38)

Entrez gene

9218

UniProt

Q9P0L0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9P0L0

Antibodypedia

VAPA antibodies

PROTEIN BROWSER

VAPA-001
VAPA-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VAPA-001
ENSP00000382880
ENST00000400000
Q9P0L0 [Direct mapping]
Vesicle-associated membrane protein-associated protein A
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0006665 [sphingolipid metabolic process]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0007165 [signal transduction]
GO:0008017 [microtubule binding]
GO:0008219 [cell death]
GO:0016021 [integral component of membrane]
GO:0019904 [protein domain specific binding]
GO:0030148 [sphingolipid biosynthetic process]
GO:0031175 [neuron projection development]
GO:0031982 [vesicle]
GO:0033149 [FFAT motif binding]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0044281 [small molecule metabolic process]
GO:0044791 [positive regulation by host of viral release from host cell]
GO:0044828 [negative regulation by host of viral genome replication]
GO:0044829 [positive regulation by host of viral genome replication]
GO:0046982 [protein heterodimerization activity]
GO:0048471 [perinuclear region of cytoplasm]
GO:0061025 [membrane fusion]
GO:0070972 [protein localization to endoplasmic reticulum]
GO:0090114 [COPII-coated vesicle budding]
Show all
249 aa
27.9 kDa
No 1
VAPA-002
ENSP00000345656
ENST00000340541
Q9P0L0 [Direct mapping]
Vesicle-associated membrane protein-associated protein A
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0006665 [sphingolipid metabolic process]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0007165 [signal transduction]
GO:0008017 [microtubule binding]
GO:0008219 [cell death]
GO:0015630 [microtubule cytoskeleton]
GO:0016021 [integral component of membrane]
GO:0019904 [protein domain specific binding]
GO:0030148 [sphingolipid biosynthetic process]
GO:0031175 [neuron projection development]
GO:0031982 [vesicle]
GO:0033149 [FFAT motif binding]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0044281 [small molecule metabolic process]
GO:0044791 [positive regulation by host of viral release from host cell]
GO:0044828 [negative regulation by host of viral genome replication]
GO:0044829 [positive regulation by host of viral genome replication]
GO:0046982 [protein heterodimerization activity]
GO:0048471 [perinuclear region of cytoplasm]
GO:0061025 [membrane fusion]
GO:0070972 [protein localization to endoplasmic reticulum]
GO:0090114 [COPII-coated vesicle budding]
Show all
294 aa
32.6 kDa
No 1

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