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RNMT

GENERAL INFORMATION

Gene name

 RNMT

Gene description

 RNA (guanine-7-) methyltransferase

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear and cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA039409
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RNMT (HGNC Symbol)

Synonyms

 RG7MT1

Description

 RNA (guanine-7-) methyltransferase (HGNC Symbol)

Entrez gene summary

Chromosome

 18

Cytoband

 p11.21

Chromosome location (bp)

 13726660 - 13764558

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000101654 (version 83.38)

Entrez gene

 8731

UniProt

 O43148 (UniProt - Evidence at protein level)

neXtProt

 NX_O43148

Antibodypedia

 RNMT antibodies

PROTEIN BROWSER
RNMT-001
RNMT-003
RNMT-005
RNMT-006
RNMT-007
RNMT-009
RNMT-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RNMT-001
ENSP00000372804
ENST00000383314
O43148 [Direct mapping]
mRNA cap guanine-N7 methyltransferase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0004482 [mRNA (guanine-N7-)-methyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005845 [mRNA cap binding complex]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006370 [7-methylguanosine mRNA capping]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0036265 [RNA (guanine-N7)-methylation]
GO:0043235 [receptor complex]
Show all
 476 aa
54.8 kDa 		No 0
RNMT-003
ENSP00000446426
ENST00000543302
O43148 [Direct mapping]
mRNA cap guanine-N7 methyltransferase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0004482 [mRNA (guanine-N7-)-methyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005845 [mRNA cap binding complex]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006370 [7-methylguanosine mRNA capping]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0036265 [RNA (guanine-N7)-methylation]
GO:0043235 [receptor complex]
Show all
 476 aa
54.8 kDa 		No 0
RNMT-005
ENSP00000466111
ENST00000592764
O43148 [Direct mapping]
mRNA cap guanine-N7 methyltransferase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0004482 [mRNA (guanine-N7-)-methyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005845 [mRNA cap binding complex]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006370 [7-methylguanosine mRNA capping]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0036265 [RNA (guanine-N7)-methylation]
GO:0043235 [receptor complex]
Show all
 504 aa
57.7 kDa 		No 0
RNMT-006
ENSP00000467475
ENST00000591746
K7EPP5 [Direct mapping]
mRNA cap guanine-N7 methyltransferase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 101 aa
11.1 kDa 		No 0
RNMT-007
ENSP00000466252
ENST00000589866
O43148 [Direct mapping]
mRNA cap guanine-N7 methyltransferase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0004482 [mRNA (guanine-N7-)-methyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005845 [mRNA cap binding complex]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006370 [7-methylguanosine mRNA capping]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0036265 [RNA (guanine-N7)-methylation]
GO:0043235 [receptor complex]
Show all
 476 aa
54.8 kDa 		No 0
RNMT-009
ENSP00000468261
ENST00000593007
K7ERH6 [Direct mapping]
mRNA cap guanine-N7 methyltransferase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 114 aa
13 kDa 		No 0
RNMT-201
ENSP00000262173
ENST00000262173
O43148 [Direct mapping]
mRNA cap guanine-N7 methyltransferase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0004482 [mRNA (guanine-N7-)-methyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005845 [mRNA cap binding complex]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006370 [7-methylguanosine mRNA capping]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0036265 [RNA (guanine-N7)-methylation]
GO:0043235 [receptor complex]
Show all
 476 aa
54.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.