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DHRS12

GENERAL INFORMATION

Gene name

 DHRS12

Gene description

 Dehydrogenase/reductase (SDR family) member 12

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Uncertain based on 2 antibodies.
HPA057028 , CAB034238
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 DHRS12 (HGNC Symbol)

Synonyms

 FLJ13639, SDR40C1

Description

 Dehydrogenase/reductase (SDR family) member 12 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family, which has over 46,000 members. Members in this family are enzymes that metabolize many different compounds, such as steroid hormones, prostaglandins, retinoids, lipids and xenobiotics. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]

Chromosome

 13

Cytoband

 q14.3

Chromosome location (bp)

 51767993 - 51804157

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000102796 (version 83.38)

Entrez gene

 79758

UniProt

 A0PJE2 (UniProt - Evidence at transcript level)

neXtProt

 NX_A0PJE2

Antibodypedia

 DHRS12 antibodies

PROTEIN BROWSER
DHRS12-001
DHRS12-002
DHRS12-005
DHRS12-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DHRS12-001
ENSP00000218981
ENST00000218981
A0PJE2 [Direct mapping]
Dehydrogenase/reductase SDR family member 12
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Predicted intracellular proteins
Show all
GO:0008152 [metabolic process]
GO:0016491 [oxidoreductase activity]
GO:0055114 [oxidation-reduction process]
Show all
 242 aa
27.1 kDa 		No 0
DHRS12-002
ENSP00000411565
ENST00000444610
A0PJE2 [Direct mapping]
Dehydrogenase/reductase SDR family member 12
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   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0008152 [metabolic process]
GO:0016491 [oxidoreductase activity]
GO:0055114 [oxidation-reduction process]
Show all
 317 aa
35.1 kDa 		No 0
DHRS12-005
ENSP00000478573
ENST00000461948
A0A087WUE0 [Direct mapping]
Dehydrogenase/reductase SDR family member 12
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   Phobius predicted membrane proteins
Predicted intracellular proteins
Show all
 100 aa
10.8 kDa 		No 0
DHRS12-007
ENSP00000280056
ENST00000280056
A0PJE2 [Direct mapping]
Dehydrogenase/reductase SDR family member 12
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0008152 [metabolic process]
GO:0016491 [oxidoreductase activity]
GO:0055114 [oxidation-reduction process]
Show all
 271 aa
30.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.