Cell atlas - OLFM4 - The Human Protein Atlas

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OLFM4

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	OLFM4
Gene description	Olfactomedin 4
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (HaCaT, BJ hTERT+)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HaCaT, BJ hTERT+) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	OLFM4 (HGNC Symbol)
Synonyms	GC1, GW112, OlfD
Description	Olfactomedin 4 (HGNC Symbol)
Entrez gene summary	This gene was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion. [provided by RefSeq, Mar 2011]
Chromosome	13
Cytoband	q14.3
Chromosome location (bp)	53028759 - 53052057
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000102837 (version 83.38)
Entrez gene	10562
UniProt	Q6UX06 (UniProt - Evidence at protein level)
neXtProt	NX_Q6UX06
Antibodypedia	OLFM4 antibodies

PROTEIN BROWSER

OLFM4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OLFM4-001 ENSP00000219022 ENST00000219022	Q6UX06 [Direct mapping] Olfactomedin-4 A0A024QZ95 [Target identity:100%; Query identity:100%] Olfactomedin 4, isoform CRA_a Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005739 [mitochondrion] GO:0005886 [plasma membrane] GO:0007155 [cell adhesion] GO:0008152 [metabolic process] GO:0042581 [specific granule] GO:0042803 [protein homodimerization activity] GO:0043124 [negative regulation of I-kappaB kinase/NF-kappaB signaling] GO:0045296 [cadherin binding] GO:0048471 [perinuclear region of cytoplasm] GO:0050777 [negative regulation of immune response] GO:0051260 [protein homooligomerization] GO:0070062 [extracellular exosome] GO:1900026 [positive regulation of substrate adhesion-dependent cell spreading] Show all	510 aa 57.3 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.