Tissue expression of OLFM4 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	OLFM4
Gene description	Olfactomedin 4
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (small intestine, duodenum, rectum)
GTEx:	Group enriched (small intestine, pancreas, vagina)
FANTOM5:	Tissue enhanced (small intestine, colon)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (small intestine, duodenum, rectum)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (small intestine, pancreas, vagina)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (small intestine, colon)

GENE INFORMATION
Gene name	OLFM4 (HGNC Symbol)
Synonyms	GC1, GW112, OlfD
Description	Olfactomedin 4 (HGNC Symbol)
Entrez gene summary	This gene was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion. [provided by RefSeq, Mar 2011]
Chromosome	13
Cytoband	q14.3
Chromosome location (bp)	53028759 - 53052057
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000102837 (version 83.38)
Entrez gene	10562
UniProt	Q6UX06 (UniProt - Evidence at protein level)
neXtProt	NX_Q6UX06
Antibodypedia	OLFM4 antibodies

PROTEIN BROWSER

OLFM4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OLFM4-001 ENSP00000219022 ENST00000219022	Q6UX06 [Direct mapping] Olfactomedin-4 A0A024QZ95 [Target identity:100%; Query identity:100%] Olfactomedin 4, isoform CRA_a Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005739 [mitochondrion] GO:0005886 [plasma membrane] GO:0007155 [cell adhesion] GO:0008152 [metabolic process] GO:0042581 [specific granule] GO:0042803 [protein homodimerization activity] GO:0043124 [negative regulation of I-kappaB kinase/NF-kappaB signaling] GO:0045296 [cadherin binding] GO:0048471 [perinuclear region of cytoplasm] GO:0050777 [negative regulation of immune response] GO:0051260 [protein homooligomerization] GO:0070062 [extracellular exosome] GO:1900026 [positive regulation of substrate adhesion-dependent cell spreading] Show all	510 aa 57.3 kDa	Yes	0