Tissue expression of LYRM1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	LYRM1
Gene description	LYR motif containing 1
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	LYRM1 (HGNC Symbol)
Synonyms	A211C6.1
Description	LYR motif containing 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Chromosome	16
Cytoband	p12.3
Chromosome location (bp)	20899868 - 20925006
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000102897 (version 83.38)
Entrez gene	57149
UniProt	O43325 (UniProt - Evidence at transcript level)
neXtProt	NX_O43325
Antibodypedia	LYRM1 antibodies

PROTEIN BROWSER

LYRM1-001	LYRM1-002	LYRM1-005	LYRM1-006	LYRM1-008	LYRM1-009	LYRM1-201	LYRM1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LYRM1-001 ENSP00000379367 ENST00000396052	O43325 [Direct mapping] LYR motif-containing protein 1 A0A024R3C2 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0045171 [intercellular bridge] Show all	122 aa 14.3 kDa	No	0
LYRM1-002 ENSP00000396868 ENST00000412082	H3BNA8 [Direct mapping] LYR motif-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		33 aa 3.8 kDa	No	0
LYRM1-005 ENSP00000454759 ENST00000562740	H3BNA8 [Direct mapping] LYR motif-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		33 aa 3.8 kDa	No	0
LYRM1-006 ENSP00000457333 ENST00000567954	O43325 [Direct mapping] LYR motif-containing protein 1 A0A024R3C2 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0045171 [intercellular bridge] Show all	122 aa 14.3 kDa	No	0
LYRM1-008 ENSP00000454826 ENST00000568663	O43325 [Direct mapping] LYR motif-containing protein 1 A0A024R3C2 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0045171 [intercellular bridge] Show all	122 aa 14.3 kDa	No	0
LYRM1-009 ENSP00000454551 ENST00000569023	O43325 [Direct mapping] LYR motif-containing protein 1 A0A024R3C2 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0045171 [intercellular bridge] Show all	122 aa 14.3 kDa	No	0
LYRM1-201 ENSP00000219168 ENST00000219168	O43325 [Direct mapping] LYR motif-containing protein 1 A0A024R3C2 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0045171 [intercellular bridge] Show all	122 aa 14.3 kDa	No	0
LYRM1-202 ENSP00000407883 ENST00000439021	O43325 [Direct mapping] LYR motif-containing protein 1 A0A024R3C2 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0045171 [intercellular bridge] Show all	122 aa 14.3 kDa	No	0