Cell atlas - ARL2BP - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ARL2BP

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	ARL2BP
Gene description	ADP-ribosylation factor-like 2 binding protein
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ARL2BP (HGNC Symbol)
Synonyms	BART, BART1, RP66
Description	ADP-ribosylation factor-like 2 binding protein (HGNC Symbol)
Entrez gene summary	ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008]
Chromosome	16
Cytoband	q13
Chromosome location (bp)	57245098 - 57253635
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000102931 (version 83.38)
Entrez gene	23568
UniProt	Q9Y2Y0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y2Y0
Antibodypedia	ARL2BP antibodies

PROTEIN BROWSER

ARL2BP-001	ARL2BP-002	ARL2BP-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARL2BP-001 ENSP00000219204 ENST00000219204	Q9Y2Y0 [Direct mapping] ADP-ribosylation factor-like protein 2-binding protein A0A024R6U9 [Target identity:100%; Query identity:100%] ADP-ribosylation factor-like 2 binding protein, isoform CRA_a Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005758 [mitochondrial intermembrane space] GO:0005759 [mitochondrial matrix] GO:0005813 [centrosome] GO:0005819 [spindle] GO:0005829 [cytosol] GO:0005929 [cilium] GO:0006112 [energy reserve metabolic process] GO:0007165 [signal transduction] GO:0030496 [midbody] GO:0030695 [GTPase regulator activity] GO:0042517 [positive regulation of tyrosine phosphorylation of Stat3 protein] GO:0044281 [small molecule metabolic process] GO:0050790 [regulation of catalytic activity] GO:0050796 [regulation of insulin secretion] GO:0051457 [maintenance of protein location in nucleus] GO:1903506 [regulation of nucleic acid-templated transcription] Show all	163 aa 18.8 kDa	No	0
ARL2BP-002 ENSP00000454237 ENST00000563234	H3BM52 [Direct mapping] ADP-ribosylation factor-like protein 2-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		171 aa 19.7 kDa	No	0
ARL2BP-005 ENSP00000457465 ENST00000562023	H3BU49 [Direct mapping] ADP-ribosylation factor-like protein 2-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		123 aa 13.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.