Expression of PRSS54 in cancer - Summary

CANCER ATLAS

Gene description

Protease, serine, 54

Protein class

Enzymes, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041549

GENE INFORMATION
Gene name	PRSS54 (HGNC Symbol)
Synonyms	CT67, FLJ25339, KLKBL4
Description	Protease, serine, 54 (HGNC Symbol)
Entrez gene summary	This gene encodes a putative serine-type endopeptidase containing the peptidase S1 domain. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Chromosome	16
Cytoband	q21
Chromosome location (bp)	58279997 - 58295047
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000103023 (version 83.38)
Entrez gene	221191
UniProt	Q6PEW0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6PEW0
Antibodypedia	PRSS54 antibodies

PROTEIN BROWSER

PRSS54-001	PRSS54-002	PRSS54-003	PRSS54-005	PRSS54-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRSS54-001 ENSP00000455024 ENST00000567164	Q6PEW0 [Direct mapping] Inactive serine protease 54 Show all	Enzymes Peptidases Serine-type peptidases Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	395 aa 43.8 kDa	Yes	0
PRSS54-002 ENSP00000437705 ENST00000543437	F5H6C6 [Direct mapping] Inactive serine protease 54 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	296 aa 33.3 kDa	No	0
PRSS54-003 ENSP00000455921 ENST00000569079	H3BQS7 [Direct mapping] Inactive serine protease 54 Show all	Predicted intracellular proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	203 aa 22.9 kDa	No	0
PRSS54-005 ENSP00000455055 ENST00000569727	H3BNY0 [Direct mapping] Inactive serine protease 54 Show all	SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	186 aa 20.3 kDa	Yes	0
PRSS54-201 ENSP00000219301 ENST00000219301	Q6PEW0 [Direct mapping] Inactive serine protease 54 Show all	Enzymes Peptidases Serine-type peptidases Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	395 aa 43.8 kDa	Yes	0