Tissue expression of PRSS54 - Summary - The Human Protein Atlas

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PRSS54

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	PRSS54
Gene description	Protease, serine, 54
Protein class	Enzymes Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending retesting.
Reliability score	Uncertain based on 1 antibody. HPA041549
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	PRSS54 (HGNC Symbol)
Synonyms	CT67, FLJ25339, KLKBL4
Description	Protease, serine, 54 (HGNC Symbol)
Entrez gene summary	This gene encodes a putative serine-type endopeptidase containing the peptidase S1 domain. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Chromosome	16
Cytoband	q21
Chromosome location (bp)	58279997 - 58295047
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000103023 (version 83.38)
Entrez gene	221191
UniProt	Q6PEW0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6PEW0
Antibodypedia	PRSS54 antibodies

PROTEIN BROWSER

PRSS54-001	PRSS54-002	PRSS54-003	PRSS54-005	PRSS54-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRSS54-001 ENSP00000455024 ENST00000567164	Q6PEW0 [Direct mapping] Inactive serine protease 54 Show all	Enzymes Peptidases Serine-type peptidases Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	395 aa 43.8 kDa	Yes	0
PRSS54-002 ENSP00000437705 ENST00000543437	F5H6C6 [Direct mapping] Inactive serine protease 54 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	296 aa 33.3 kDa	No	0
PRSS54-003 ENSP00000455921 ENST00000569079	H3BQS7 [Direct mapping] Inactive serine protease 54 Show all	Predicted intracellular proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	203 aa 22.9 kDa	No	0
PRSS54-005 ENSP00000455055 ENST00000569727	H3BNY0 [Direct mapping] Inactive serine protease 54 Show all	SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	186 aa 20.3 kDa	Yes	0
PRSS54-201 ENSP00000219301 ENST00000219301	Q6PEW0 [Direct mapping] Inactive serine protease 54 Show all	Enzymes Peptidases Serine-type peptidases Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	395 aa 43.8 kDa	Yes	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.