Expression of ACSBG1 in cancer - Summary

CANCER ATLAS

Gene description

Acyl-CoA synthetase bubblegum family member 1

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Melanoma

STAINING SUMMARY

HPA041642	CAB045955

GENE INFORMATION
Gene name	ACSBG1 (HGNC Symbol)
Synonyms	BG1, BGM, FLJ30320, hBG1, hsBG, KIAA0631, MGC14352
Description	Acyl-CoA synthetase bubblegum family member 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. [provided by RefSeq, Jul 2008]
Chromosome	15
Cytoband	q25.1
Chromosome location (bp)	78167468 - 78245688
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000103740 (version 83.38)
Entrez gene	23205
UniProt	Q96GR2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96GR2
Antibodypedia	ACSBG1 antibodies

PROTEIN BROWSER

ACSBG1-001	ACSBG1-007	ACSBG1-010	ACSBG1-013	ACSBG1-014

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACSBG1-001 ENSP00000258873 ENST00000258873	Q96GR2 [Direct mapping] Long-chain-fatty-acid--CoA ligase ACSBG1 Show all	Enzymes ENZYME proteins Ligase MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0000038 [very long-chain fatty acid metabolic process] GO:0001552 [ovarian follicle atresia] GO:0001676 [long-chain fatty acid metabolic process] GO:0003824 [catalytic activity] GO:0004467 [long-chain fatty acid-CoA ligase activity] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0008152 [metabolic process] GO:0016023 [cytoplasmic membrane-bounded vesicle] GO:0019432 [triglyceride biosynthetic process] GO:0031957 [very long-chain fatty acid-CoA ligase activity] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0042552 [myelination] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0051384 [response to glucocorticoid] Show all	724 aa 81.3 kDa	No	0
ACSBG1-007 ENSP00000453547 ENST00000559241	H0YMC3 [Direct mapping] Long-chain-fatty-acid--CoA ligase ACSBG1 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	243 aa 27.6 kDa	No	0
ACSBG1-010 ENSP00000453451 ENST00000560817	F5H4U6 [Direct mapping] Long-chain-fatty-acid--CoA ligase ACSBG1 Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	482 aa 53.9 kDa	No	0
ACSBG1-013 ENSP00000454188 ENST00000559114	H0YNX0 [Direct mapping] Long-chain-fatty-acid--CoA ligase ACSBG1 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	139 aa 15.7 kDa	No	0
ACSBG1-014 ENSP00000453800 ENST00000558130	H0YMZ0 [Direct mapping] Long-chain-fatty-acid--CoA ligase ACSBG1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	182 aa 20.5 kDa	No	0