Cell atlas - ACSBG1 - The Human Protein Atlas

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ACSBG1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Vesicles

Human cell
	Vesicles

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GENERAL INFORMATION
Gene name	ACSBG1
Gene description	Acyl-CoA synthetase bubblegum family member 1
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to vesicles.
RNA cell category	Cell line enhanced (NTERA-2)
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA058869
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (NTERA-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to vesicles.

Main location

Vesicles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA058869	HEK 293	Vesicles
	HPA058869	SK-MEL-30	Nucleus
	HPA058869	SK-MEL-30	Vesicles
	HPA058869	U-2 OS	Nucleus
	HPA058869	U-2 OS	Vesicles

GENE INFORMATION
Gene name	ACSBG1 (HGNC Symbol)
Synonyms	BG1, BGM, FLJ30320, hBG1, hsBG, KIAA0631, MGC14352
Description	Acyl-CoA synthetase bubblegum family member 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. [provided by RefSeq, Jul 2008]
Chromosome	15
Cytoband	q25.1
Chromosome location (bp)	78167468 - 78245688
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000103740 (version 83.38)
Entrez gene	23205
UniProt	Q96GR2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96GR2
Antibodypedia	ACSBG1 antibodies

PROTEIN BROWSER

ACSBG1-001	ACSBG1-007	ACSBG1-010	ACSBG1-013	ACSBG1-014

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACSBG1-001 ENSP00000258873 ENST00000258873	Q96GR2 [Direct mapping] Long-chain-fatty-acid--CoA ligase ACSBG1 Show all	Enzymes ENZYME proteins Ligase MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0000038 [very long-chain fatty acid metabolic process] GO:0001552 [ovarian follicle atresia] GO:0001676 [long-chain fatty acid metabolic process] GO:0003824 [catalytic activity] GO:0004467 [long-chain fatty acid-CoA ligase activity] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0008152 [metabolic process] GO:0016023 [cytoplasmic membrane-bounded vesicle] GO:0019432 [triglyceride biosynthetic process] GO:0031957 [very long-chain fatty acid-CoA ligase activity] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0042552 [myelination] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0051384 [response to glucocorticoid] Show all	724 aa 81.3 kDa	No	0
ACSBG1-007 ENSP00000453547 ENST00000559241	H0YMC3 [Direct mapping] Long-chain-fatty-acid--CoA ligase ACSBG1 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	243 aa 27.6 kDa	No	0
ACSBG1-010 ENSP00000453451 ENST00000560817	F5H4U6 [Direct mapping] Long-chain-fatty-acid--CoA ligase ACSBG1 Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	482 aa 53.9 kDa	No	0
ACSBG1-013 ENSP00000454188 ENST00000559114	H0YNX0 [Direct mapping] Long-chain-fatty-acid--CoA ligase ACSBG1 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	139 aa 15.7 kDa	No	0
ACSBG1-014 ENSP00000453800 ENST00000558130	H0YMZ0 [Direct mapping] Long-chain-fatty-acid--CoA ligase ACSBG1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	182 aa 20.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.