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NCALD

CANCER ATLAS

Gene description

 Neurocalcin delta

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA043245

GENE INFORMATION

Gene name

 NCALD

Synonyms

Description

 Neurocalcin delta (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

 8

Cytoband

 q22.3

Chromosome location (bp)

 101686543 - 102124907

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000104490 (version 83.38)

Entrez gene

 83988

UniProt

 P61601 (UniProt - Evidence at protein level)

neXtProt

 NX_P61601

Antibodypedia

 NCALD antibodies

PROTEIN BROWSER
«
NCALD-001
NCALD-002
NCALD-003
NCALD-007
NCALD-008
NCALD-009
NCALD-010
NCALD-011
NCALD-012
NCALD-013
NCALD-014
NCALD-015
NCALD-016
NCALD-017
NCALD-019
NCALD-023
NCALD-026
NCALD-027
NCALD-028
NCALD-029
NCALD-030
NCALD-031
NCALD-201
NCALD-202
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NCALD-001
ENSP00000428105
ENST00000521599
P61601 [Direct mapping]
Neurocalcin-delta
B2RB70 [Target identity:100%; Query identity:100%]
Neurocalcin delta, isoform CRA_a; cDNA FLJ30511 fis, clone BRAWH2000636, highly similar to NEUROCALCIN DELTA; cDNA FLJ39196 fis, clone OCBBF2005066, highly similar to NEUROCALCIN DELTA; cDNA, FLJ95342, highly similar to Homo sapiens neurocalcin delta (NCALD), mRNA
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0007268 [synaptic transmission]
GO:0015631 [tubulin binding]
GO:0016192 [vesicle-mediated transport]
GO:0030130 [clathrin coat of trans-Golgi network vesicle]
GO:0030276 [clathrin binding]
GO:0070062 [extracellular exosome]
Show all
 193 aa
22.2 kDa 		No 0
NCALD-002
ENSP00000428781
ENST00000522951
E5RGA9 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 194 aa
22.4 kDa 		No 0
NCALD-003
ENSP00000220931
ENST00000220931
P61601 [Direct mapping]
Neurocalcin-delta
B2RB70 [Target identity:100%; Query identity:100%]
Neurocalcin delta, isoform CRA_a; cDNA FLJ30511 fis, clone BRAWH2000636, highly similar to NEUROCALCIN DELTA; cDNA FLJ39196 fis, clone OCBBF2005066, highly similar to NEUROCALCIN DELTA; cDNA, FLJ95342, highly similar to Homo sapiens neurocalcin delta (NCALD), mRNA
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0007268 [synaptic transmission]
GO:0015631 [tubulin binding]
GO:0016192 [vesicle-mediated transport]
GO:0030130 [clathrin coat of trans-Golgi network vesicle]
GO:0030276 [clathrin binding]
GO:0070062 [extracellular exosome]
Show all
 193 aa
22.2 kDa 		No 0
NCALD-007
ENSP00000430476
ENST00000519508
P61601 [Direct mapping]
Neurocalcin-delta
B2RB70 [Target identity:100%; Query identity:100%]
Neurocalcin delta, isoform CRA_a; cDNA FLJ30511 fis, clone BRAWH2000636, highly similar to NEUROCALCIN DELTA; cDNA FLJ39196 fis, clone OCBBF2005066, highly similar to NEUROCALCIN DELTA; cDNA, FLJ95342, highly similar to Homo sapiens neurocalcin delta (NCALD), mRNA
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0007268 [synaptic transmission]
GO:0015631 [tubulin binding]
GO:0016192 [vesicle-mediated transport]
GO:0030130 [clathrin coat of trans-Golgi network vesicle]
GO:0030276 [clathrin binding]
GO:0070062 [extracellular exosome]
Show all
 193 aa
22.2 kDa 		No 0
NCALD-008
ENSP00000429162
ENST00000522078
E5RJA1 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 14 aa
1.6 kDa 		No 0
NCALD-009
ENSP00000429296
ENST00000522206
E5RIX3 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 52 aa
6.3 kDa 		No 0
NCALD-010
ENSP00000429522
ENST00000518166
E5RI78 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 116 aa
13.5 kDa 		No 0
NCALD-011
ENSP00000430064
ENST00000521964
E5RGZ0 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 87 aa
10.2 kDa 		No 0
NCALD-012
ENSP00000429245
ENST00000517531
E5RI95 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 105 aa
12.3 kDa 		No 0
NCALD-013
ENSP00000428093
ENST00000518661
E5RK89 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 74 aa
8.8 kDa 		No 0
NCALD-014
ENSP00000430925
ENST00000520425
E5RHC8 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 120 aa
13.9 kDa 		No 0
NCALD-015
ENSP00000430731
ENST00000518727
E5RIG4 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 122 aa
14.2 kDa 		No 0
NCALD-016
ENSP00000428193
ENST00000523923
E5RJT1 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 81 aa
9.4 kDa 		No 0
NCALD-017
ENSP00000428312
ENST00000517822
E5RHE8 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 112 aa
13.1 kDa 		No 0
NCALD-019
ENSP00000429255
ENST00000520690
E5RIZ1 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 136 aa
15.7 kDa 		No 0
NCALD-023
ENSP00000428598
ENST00000522252
E5RHE8 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 112 aa
13.1 kDa 		No 0
NCALD-026
ENSP00000429347
ENST00000523645
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 3 aa
0.3 kDa 		No 0
NCALD-027
ENSP00000430578
ENST00000524137
E5RJF1 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 15 aa
1.8 kDa 		No 0
NCALD-028
ENSP00000429493
ENST00000524209
E5RI95 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 105 aa
12.3 kDa 		No 0
NCALD-029
ENSP00000430534
ENST00000519098
E5RJJ6 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 85 aa
10 kDa 		No 0
NCALD-030
ENSP00000430365
ENST00000520346
E5RFL9 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 78 aa
9.1 kDa 		No 0
NCALD-031
ENSP00000429466
ENST00000522448
E5RIA5 [Direct mapping]
Neurocalcin-delta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 152 aa
17.8 kDa 		No 0
NCALD-201
ENSP00000310587
ENST00000311028
P61601 [Direct mapping]
Neurocalcin-delta
B2RB70 [Target identity:100%; Query identity:100%]
Neurocalcin delta, isoform CRA_a; cDNA FLJ30511 fis, clone BRAWH2000636, highly similar to NEUROCALCIN DELTA; cDNA FLJ39196 fis, clone OCBBF2005066, highly similar to NEUROCALCIN DELTA; cDNA, FLJ95342, highly similar to Homo sapiens neurocalcin delta (NCALD), mRNA
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0007268 [synaptic transmission]
GO:0015631 [tubulin binding]
GO:0016192 [vesicle-mediated transport]
GO:0030130 [clathrin coat of trans-Golgi network vesicle]
GO:0030276 [clathrin binding]
GO:0070062 [extracellular exosome]
Show all
 193 aa
22.2 kDa 		No 0
NCALD-202
ENSP00000379256
ENST00000395923
P61601 [Direct mapping]
Neurocalcin-delta
B2RB70 [Target identity:100%; Query identity:100%]
Neurocalcin delta, isoform CRA_a; cDNA FLJ30511 fis, clone BRAWH2000636, highly similar to NEUROCALCIN DELTA; cDNA FLJ39196 fis, clone OCBBF2005066, highly similar to NEUROCALCIN DELTA; cDNA, FLJ95342, highly similar to Homo sapiens neurocalcin delta (NCALD), mRNA
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003073 [regulation of systemic arterial blood pressure]
GO:0003779 [actin binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0007268 [synaptic transmission]
GO:0015631 [tubulin binding]
GO:0016192 [vesicle-mediated transport]
GO:0019722 [calcium-mediated signaling]
GO:0030130 [clathrin coat of trans-Golgi network vesicle]
GO:0030276 [clathrin binding]
GO:0043014 [alpha-tubulin binding]
GO:0070062 [extracellular exosome]
Show all
 193 aa
22.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.