Cell atlas - NCALD - The Human Protein Atlas

GENERAL INFORMATION
Gene name	NCALD
Gene description	Neurocalcin delta
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	24
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HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Group enriched (HDLM-2, AF22)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (HDLM-2, AF22) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	NCALD
Synonyms
Description	Neurocalcin delta (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Chromosome	8
Cytoband	q22.3
Chromosome location (bp)	101686543 - 102124907
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000104490 (version 83.38)
Entrez gene	83988
UniProt	P61601 (UniProt - Evidence at protein level)
neXtProt	NX_P61601
Antibodypedia	NCALD antibodies

PROTEIN BROWSER

NCALD-001	NCALD-002	NCALD-003	NCALD-007	NCALD-008	NCALD-009	NCALD-010	NCALD-011	NCALD-012	NCALD-013	NCALD-014	NCALD-015	NCALD-016	NCALD-017	NCALD-019	NCALD-023	NCALD-026	NCALD-027	NCALD-028	NCALD-029	NCALD-030	NCALD-031	NCALD-201	NCALD-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NCALD-001 ENSP00000428105 ENST00000521599	P61601 [Direct mapping] Neurocalcin-delta B2RB70 [Target identity:100%; Query identity:100%] Neurocalcin delta, isoform CRA_a; cDNA FLJ30511 fis, clone BRAWH2000636, highly similar to NEUROCALCIN DELTA; cDNA FLJ39196 fis, clone OCBBF2005066, highly similar to NEUROCALCIN DELTA; cDNA, FLJ95342, highly similar to Homo sapiens neurocalcin delta (NCALD), mRNA Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003779 [actin binding] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0007268 [synaptic transmission] GO:0015631 [tubulin binding] GO:0016192 [vesicle-mediated transport] GO:0030130 [clathrin coat of trans-Golgi network vesicle] GO:0030276 [clathrin binding] GO:0070062 [extracellular exosome] Show all	193 aa 22.2 kDa	No	0
NCALD-002 ENSP00000428781 ENST00000522951	E5RGA9 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	194 aa 22.4 kDa	No	0
NCALD-003 ENSP00000220931 ENST00000220931	P61601 [Direct mapping] Neurocalcin-delta B2RB70 [Target identity:100%; Query identity:100%] Neurocalcin delta, isoform CRA_a; cDNA FLJ30511 fis, clone BRAWH2000636, highly similar to NEUROCALCIN DELTA; cDNA FLJ39196 fis, clone OCBBF2005066, highly similar to NEUROCALCIN DELTA; cDNA, FLJ95342, highly similar to Homo sapiens neurocalcin delta (NCALD), mRNA Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003779 [actin binding] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0007268 [synaptic transmission] GO:0015631 [tubulin binding] GO:0016192 [vesicle-mediated transport] GO:0030130 [clathrin coat of trans-Golgi network vesicle] GO:0030276 [clathrin binding] GO:0070062 [extracellular exosome] Show all	193 aa 22.2 kDa	No	0
NCALD-007 ENSP00000430476 ENST00000519508	P61601 [Direct mapping] Neurocalcin-delta B2RB70 [Target identity:100%; Query identity:100%] Neurocalcin delta, isoform CRA_a; cDNA FLJ30511 fis, clone BRAWH2000636, highly similar to NEUROCALCIN DELTA; cDNA FLJ39196 fis, clone OCBBF2005066, highly similar to NEUROCALCIN DELTA; cDNA, FLJ95342, highly similar to Homo sapiens neurocalcin delta (NCALD), mRNA Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003779 [actin binding] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0007268 [synaptic transmission] GO:0015631 [tubulin binding] GO:0016192 [vesicle-mediated transport] GO:0030130 [clathrin coat of trans-Golgi network vesicle] GO:0030276 [clathrin binding] GO:0070062 [extracellular exosome] Show all	193 aa 22.2 kDa	No	0
NCALD-008 ENSP00000429162 ENST00000522078	E5RJA1 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		14 aa 1.6 kDa	No	0
NCALD-009 ENSP00000429296 ENST00000522206	E5RIX3 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	52 aa 6.3 kDa	No	0
NCALD-010 ENSP00000429522 ENST00000518166	E5RI78 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	116 aa 13.5 kDa	No	0
NCALD-011 ENSP00000430064 ENST00000521964	E5RGZ0 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	87 aa 10.2 kDa	No	0
NCALD-012 ENSP00000429245 ENST00000517531	E5RI95 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	105 aa 12.3 kDa	No	0
NCALD-013 ENSP00000428093 ENST00000518661	E5RK89 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	74 aa 8.8 kDa	No	0
NCALD-014 ENSP00000430925 ENST00000520425	E5RHC8 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	120 aa 13.9 kDa	No	0
NCALD-015 ENSP00000430731 ENST00000518727	E5RIG4 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	122 aa 14.2 kDa	No	0
NCALD-016 ENSP00000428193 ENST00000523923	E5RJT1 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	81 aa 9.4 kDa	No	0
NCALD-017 ENSP00000428312 ENST00000517822	E5RHE8 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	112 aa 13.1 kDa	No	0
NCALD-019 ENSP00000429255 ENST00000520690	E5RIZ1 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	136 aa 15.7 kDa	No	0
NCALD-023 ENSP00000428598 ENST00000522252	E5RHE8 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	112 aa 13.1 kDa	No	0
NCALD-026 ENSP00000429347 ENST00000523645		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		3 aa 0.3 kDa	No	0
NCALD-027 ENSP00000430578 ENST00000524137	E5RJF1 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		15 aa 1.8 kDa	No	0
NCALD-028 ENSP00000429493 ENST00000524209	E5RI95 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	105 aa 12.3 kDa	No	0
NCALD-029 ENSP00000430534 ENST00000519098	E5RJJ6 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	85 aa 10 kDa	No	0
NCALD-030 ENSP00000430365 ENST00000520346	E5RFL9 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	78 aa 9.1 kDa	No	0
NCALD-031 ENSP00000429466 ENST00000522448	E5RIA5 [Direct mapping] Neurocalcin-delta Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	152 aa 17.8 kDa	No	0
NCALD-201 ENSP00000310587 ENST00000311028	P61601 [Direct mapping] Neurocalcin-delta B2RB70 [Target identity:100%; Query identity:100%] Neurocalcin delta, isoform CRA_a; cDNA FLJ30511 fis, clone BRAWH2000636, highly similar to NEUROCALCIN DELTA; cDNA FLJ39196 fis, clone OCBBF2005066, highly similar to NEUROCALCIN DELTA; cDNA, FLJ95342, highly similar to Homo sapiens neurocalcin delta (NCALD), mRNA Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003779 [actin binding] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0007268 [synaptic transmission] GO:0015631 [tubulin binding] GO:0016192 [vesicle-mediated transport] GO:0030130 [clathrin coat of trans-Golgi network vesicle] GO:0030276 [clathrin binding] GO:0070062 [extracellular exosome] Show all	193 aa 22.2 kDa	No	0
NCALD-202 ENSP00000379256 ENST00000395923	P61601 [Direct mapping] Neurocalcin-delta B2RB70 [Target identity:100%; Query identity:100%] Neurocalcin delta, isoform CRA_a; cDNA FLJ30511 fis, clone BRAWH2000636, highly similar to NEUROCALCIN DELTA; cDNA FLJ39196 fis, clone OCBBF2005066, highly similar to NEUROCALCIN DELTA; cDNA, FLJ95342, highly similar to Homo sapiens neurocalcin delta (NCALD), mRNA Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003073 [regulation of systemic arterial blood pressure] GO:0003779 [actin binding] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0007268 [synaptic transmission] GO:0015631 [tubulin binding] GO:0016192 [vesicle-mediated transport] GO:0019722 [calcium-mediated signaling] GO:0030130 [clathrin coat of trans-Golgi network vesicle] GO:0030276 [clathrin binding] GO:0043014 [alpha-tubulin binding] GO:0070062 [extracellular exosome] Show all	193 aa 22.2 kDa	No	0