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ANXA13

GENERAL INFORMATION

Gene name

 ANXA13

Gene description

 Annexin A13

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (duodenum, small intestine, gallbladder, fallopian tube)
GTEx:Tissue enriched (small intestine)
FANTOM5:Tissue enhanced (small intestine, gallbladder, colon)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in gastrointestinal tract, bile ducts, gallbladder, renal tubules and fallopian tube.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 4 antibodies.
HPA018535 , HPA019569 , HPA019650 , CAB025135
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Duodenum

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (duodenum, small intestine, gallbladder, fallopian tube)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (small intestine)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (small intestine, gallbladder, colon)

GENE INFORMATION

Gene name

 ANXA13 (HGNC Symbol)

Synonyms

 ANX13

Description

 Annexin A13 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

 8

Cytoband

 q24.13

Chromosome location (bp)

 123680794 - 123737407

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000104537 (version 83.38)

Entrez gene

 312

UniProt

 P27216 (UniProt - Evidence at protein level)

neXtProt

 NX_P27216

Antibodypedia

 ANXA13 antibodies

PROTEIN BROWSER
ANXA13-001
ANXA13-002
ANXA13-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ANXA13-001
ENSP00000262219
ENST00000262219
P27216 [Direct mapping]
Annexin A13
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001786 [phosphatidylserine binding]
GO:0005509 [calcium ion binding]
GO:0005544 [calcium-dependent phospholipid binding]
GO:0005615 [extracellular space]
GO:0005654 [nucleoplasm]
GO:0005886 [plasma membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0030154 [cell differentiation]
GO:0042997 [negative regulation of Golgi to plasma membrane protein transport]
GO:0042998 [positive regulation of Golgi to plasma membrane protein transport]
GO:0045121 [membrane raft]
GO:0070062 [extracellular exosome]
GO:0070382 [exocytic vesicle]
GO:1901611 [phosphatidylglycerol binding]
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 357 aa
39.7 kDa 		No 0
ANXA13-002
ENSP00000390809
ENST00000419625
P27216 [Direct mapping]
Annexin A13
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001786 [phosphatidylserine binding]
GO:0005509 [calcium ion binding]
GO:0005544 [calcium-dependent phospholipid binding]
GO:0005615 [extracellular space]
GO:0005654 [nucleoplasm]
GO:0005886 [plasma membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0030154 [cell differentiation]
GO:0042997 [negative regulation of Golgi to plasma membrane protein transport]
GO:0042998 [positive regulation of Golgi to plasma membrane protein transport]
GO:0045121 [membrane raft]
GO:0070062 [extracellular exosome]
GO:0070382 [exocytic vesicle]
GO:1901611 [phosphatidylglycerol binding]
Show all
 316 aa
35.4 kDa 		No 0
ANXA13-004
ENSP00000429358
ENST00000520519
E5RIN3 [Direct mapping]
Annexin A13
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005544 [calcium-dependent phospholipid binding]
Show all
 113 aa
12.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.