Expression of PPP1R13L in cancer - Summary

CANCER ATLAS

Gene description

Protein phosphatase 1, regulatory subunit 13 like

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041231	HPA059883	CAB005016

GENE INFORMATION
Gene name	PPP1R13L (HGNC Symbol)
Synonyms	IASPP, RAI
Description	Protein phosphatase 1, regulatory subunit 13 like (HGNC Symbol)
Entrez gene summary	IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM, Mar 2008]
Chromosome	19
Cytoband	q13.32
Chromosome location (bp)	45379634 - 45406349
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000104881 (version 83.38)
Entrez gene	10848
UniProt	Q8WUF5 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WUF5
Antibodypedia	PPP1R13L antibodies

PROTEIN BROWSER

PPP1R13L-001	PPP1R13L-002	PPP1R13L-005	PPP1R13L-006	PPP1R13L-008	PPP1R13L-009	PPP1R13L-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PPP1R13L-001 ENSP00000354218 ENST00000360957	Q8WUF5 [Direct mapping] RelA-associated inhibitor A0A024R0Q5 [Target identity:100%; Query identity:100%] Protein phosphatase 1, regulatory (Inhibitor) subunit 13 like, isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Immunoglobulin fold Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003714 [transcription corepressor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006915 [apoptotic process] GO:0008134 [transcription factor binding] GO:0030054 [cell junction] GO:0042802 [identical protein binding] GO:0045171 [intercellular bridge] Show all	828 aa 89.1 kDa	No	0
PPP1R13L-002 ENSP00000403902 ENST00000418234	Q8WUF5 [Direct mapping] RelA-associated inhibitor A0A024R0Q5 [Target identity:100%; Query identity:100%] Protein phosphatase 1, regulatory (Inhibitor) subunit 13 like, isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Immunoglobulin fold Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003215 [cardiac right ventricle morphogenesis] GO:0003229 [ventricular cardiac muscle tissue development] GO:0003714 [transcription corepressor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006915 [apoptotic process] GO:0008134 [transcription factor binding] GO:0009791 [post-embryonic development] GO:0030054 [cell junction] GO:0031076 [embryonic camera-type eye development] GO:0035264 [multicellular organism growth] GO:0042633 [hair cycle] GO:0042802 [identical protein binding] GO:0045171 [intercellular bridge] GO:0045597 [positive regulation of cell differentiation] GO:0048871 [multicellular organismal homeostasis] GO:0060048 [cardiac muscle contraction] Show all	828 aa 89.1 kDa	No	0
PPP1R13L-005 ENSP00000466730 ENST00000593226	K7EN03 [Direct mapping] RelA-associated inhibitor Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006915 [apoptotic process] GO:0008134 [transcription factor binding] GO:0030054 [cell junction] GO:0045171 [intercellular bridge] Show all	128 aa 13.9 kDa	No	0
PPP1R13L-006 ENSP00000467471 ENST00000592134	K7EPP1 [Direct mapping] RelA-associated inhibitor Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006351 [transcription, DNA-templated] GO:0006915 [apoptotic process] GO:0008134 [transcription factor binding] Show all	60 aa 6.7 kDa	No	0
PPP1R13L-008 ENSP00000466939 ENST00000591986	K7ENG6 [Direct mapping] RelA-associated inhibitor Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		29 aa 3.1 kDa	No	0
PPP1R13L-009 ENSP00000466555 ENST00000589371	K7EML6 [Direct mapping] RelA-associated inhibitor Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	90 aa 9.7 kDa	No	0
PPP1R13L-201 ENSP00000478646 ENST00000612351	A0A087WUG2 [Direct mapping] RelA-associated inhibitor Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0006351 [transcription, DNA-templated] GO:0006915 [apoptotic process] GO:0008134 [transcription factor binding] Show all	348 aa 38 kDa	No	0