Expression of PBX4 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Pre-B-cell leukemia homeobox 4

Protein class

Plasma proteins, Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA049859

GENE INFORMATION
Gene name	PBX4
Synonyms
Description	Pre-B-cell leukemia homeobox 4 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the pre-B cell leukemia transcription factor family. These proteins are homeobox proteins that play critical roles in embryonic development and cellular differentiation both as Hox cofactors and through Hox-independent pathways. The encoded protein contains a homeobox DNA-binding domain, but specific functions of the protein have not been determined. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]
Chromosome	19
Cytoband	p13.11
Chromosome location (bp)	19561707 - 19618916
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000105717 (version 83.38)
Entrez gene	80714
UniProt	Q9BYU1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BYU1
Antibodypedia	PBX4 antibodies

PROTEIN BROWSER

PBX4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PBX4-001 ENSP00000251203 ENST00000251203	Q9BYU1 [Direct mapping] Pre-B-cell leukemia transcription factor 4 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Helix-turn-helix domains Show all	GO:0001741 [XY body] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006366 [transcription from RNA polymerase II promoter] GO:0043565 [sequence-specific DNA binding] GO:0045893 [positive regulation of transcription, DNA-templated] Show all	374 aa 40.9 kDa	No	0