Expression of HOXA6 in cancer - Summary

CANCER ATLAS

Gene description

Homeobox A6

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA004203

GENE INFORMATION
Gene name	HOXA6 (HGNC Symbol)
Synonyms	HOX1, HOX1B
Description	Homeobox A6 (HGNC Symbol)
Entrez gene summary	In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	p15.2
Chromosome location (bp)	27145396 - 27150603
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000106006 (version 83.38)
Entrez gene	3203
UniProt	P31267 (UniProt - Evidence at transcript level)
neXtProt	NX_P31267
Antibodypedia	HOXA6 antibodies

PROTEIN BROWSER

HOXA6-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HOXA6-001 ENSP00000222728 ENST00000222728	P31267 [Direct mapping] Homeobox protein Hox-A6 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0009952 [anterior/posterior pattern specification] GO:0043565 [sequence-specific DNA binding] GO:0048704 [embryonic skeletal system morphogenesis] GO:0048706 [embryonic skeletal system development] Show all	233 aa 26.3 kDa	No	0