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HOXA6

GENERAL INFORMATION

Gene name

 HOXA6

Gene description

 Homeobox A6

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (fallopian tube)
GTEx:Tissue enhanced (fallopian tube)
FANTOM5:Mixed

Protein evidence

 Evidence at transcript level

Protein expression

 Nuclear expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA004203
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (fallopian tube)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (fallopian tube)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 HOXA6 (HGNC Symbol)

Synonyms

 HOX1, HOX1B

Description

 Homeobox A6 (HGNC Symbol)

Entrez gene summary

 In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. [provided by RefSeq, Jul 2008]

Chromosome

 7

Cytoband

 p15.2

Chromosome location (bp)

 27145396 - 27150603

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000106006 (version 83.38)

Entrez gene

 3203

UniProt

 P31267 (UniProt - Evidence at transcript level)

neXtProt

 NX_P31267

Antibodypedia

 HOXA6 antibodies

PROTEIN BROWSER
HOXA6-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
HOXA6-001
ENSP00000222728
ENST00000222728
P31267 [Direct mapping]
Homeobox protein Hox-A6
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Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
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GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0009952 [anterior/posterior pattern specification]
GO:0043565 [sequence-specific DNA binding]
GO:0048704 [embryonic skeletal system morphogenesis]
GO:0048706 [embryonic skeletal system development]
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 233 aa
26.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.