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MEOX2

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GENERAL INFORMATION

Gene name

 MEOX2

Gene description

 Mesenchyme homeobox 2

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (AN3-CA, U-138 MG, SCLC-21H)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (AN3-CA, U-138 MG, SCLC-21H)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 MEOX2 (HGNC Symbol)

Synonyms

 GAX, MOX2

Description

 Mesenchyme homeobox 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008]

Chromosome

 7

Cytoband

 p21.2

Chromosome location (bp)

 15611212 - 15686812

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000106511 (version 83.38)

Entrez gene

 4223

UniProt

 P50222 (UniProt - Evidence at protein level)

neXtProt

 NX_P50222

Antibodypedia

 MEOX2 antibodies

PROTEIN BROWSER
MEOX2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MEOX2-001
ENSP00000262041
ENST00000262041
P50222 [Direct mapping]
Homeobox protein MOX-2
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Protein evidence (Kim et al 2014)
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001205 [transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding]
GO:0001525 [angiogenesis]
GO:0001757 [somite specification]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007275 [multicellular organismal development]
GO:0007519 [skeletal muscle tissue development]
GO:0008015 [blood circulation]
GO:0016607 [nuclear speck]
GO:0043565 [sequence-specific DNA binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0060021 [palate development]
GO:0060173 [limb development]
GO:0070997 [neuron death]
Show all
 304 aa
33.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.