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LHPP

GENERAL INFORMATION

Gene name

 LHPP

Gene description

 Phospholysine phosphohistidine inorganic pyrophosphate phosphatase

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and nuclear expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA009163 , HPA009269
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Breast
N/A
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 LHPP (HGNC Symbol)

Synonyms

 HDHD2B

Description

 Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (HGNC Symbol)

Entrez gene summary

Chromosome

 10

Cytoband

 q26.13

Chromosome location (bp)

 124461834 - 124617888

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000107902 (version 83.38)

Entrez gene

 64077

UniProt

 Q9H008 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H008

Antibodypedia

 LHPP antibodies

PROTEIN BROWSER
LHPP-001
LHPP-003
LHPP-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
LHPP-001
ENSP00000357835
ENST00000368842
Q9H008 [Direct mapping]
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase
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Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000287 [magnesium ion binding]
GO:0004427 [inorganic diphosphatase activity]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006470 [protein dephosphorylation]
GO:0006796 [phosphate-containing compound metabolic process]
GO:0008969 [phosphohistidine phosphatase activity]
GO:0042803 [protein homodimerization activity]
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 270 aa
29.2 kDa 		No 0
LHPP-003
ENSP00000376512
ENST00000392757
Q5T1Z0 [Direct mapping]
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
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 212 aa
22.9 kDa 		No 0
LHPP-007
ENSP00000357832
ENST00000368839
Q9H008 [Direct mapping]
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0004427 [inorganic diphosphatase activity]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006470 [protein dephosphorylation]
GO:0006796 [phosphate-containing compound metabolic process]
GO:0008969 [phosphohistidine phosphatase activity]
GO:0042803 [protein homodimerization activity]
Show all
 210 aa
22.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.