Expression of GALK1 in cancer - Summary

CANCER ATLAS

Gene description

Galactokinase 1

Protein class

Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA007094	HPA016960

GENE INFORMATION
Gene name	GALK1 (HGNC Symbol)
Synonyms	GALK
Description	Galactokinase 1 (HGNC Symbol)
Entrez gene summary	Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population. [provided by RefSeq, Jul 2008]
Chromosome	17
Cytoband	q25.1
Chromosome location (bp)	75751594 - 75765711
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000108479 (version 83.38)
Entrez gene	2584
UniProt	P51570 (UniProt - Evidence at protein level)
neXtProt	NX_P51570
Antibodypedia	GALK1 antibodies

PROTEIN BROWSER

GALK1-001	GALK1-002	GALK1-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GALK1-001 ENSP00000465930 ENST00000588479	P51570 [Direct mapping] Galactokinase V9HWE7 [Target identity:100%; Query identity:100%] Epididymis secretory protein Li 19 Show all	Enzymes ENZYME proteins Transferases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004335 [galactokinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005534 [galactose binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005975 [carbohydrate metabolic process] GO:0006012 [galactose metabolic process] GO:0016020 [membrane] GO:0019388 [galactose catabolic process] GO:0019402 [galactitol metabolic process] GO:0044281 [small molecule metabolic process] GO:0046835 [carbohydrate phosphorylation] GO:0070062 [extracellular exosome] Show all	392 aa 42.3 kDa	No	0
GALK1-002 ENSP00000225614 ENST00000225614	P51570 [Direct mapping] Galactokinase V9HWE7 [Target identity:100%; Query identity:100%] Epididymis secretory protein Li 19 Show all	Enzymes ENZYME proteins Transferases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Ezkurdia et al 2014) Show all	GO:0004335 [galactokinase activity] GO:0005524 [ATP binding] GO:0005534 [galactose binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005975 [carbohydrate metabolic process] GO:0006012 [galactose metabolic process] GO:0016020 [membrane] GO:0019388 [galactose catabolic process] GO:0044281 [small molecule metabolic process] GO:0046835 [carbohydrate phosphorylation] GO:0070062 [extracellular exosome] Show all	392 aa 42.3 kDa	No	0
GALK1-007 ENSP00000464765 ENST00000592997	K7EII7 [Direct mapping] Galactokinase Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		184 aa 20.1 kDa	No	0