Cell atlas - DHRS7B - The Human Protein Atlas

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DHRS7B

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cell Junctions
	Cytosol
	Plasma membrane

Human cell
	Cytosol
	Plasma Membrane

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GENERAL INFORMATION
Gene name	DHRS7B
Gene description	Dehydrogenase/reductase (SDR family) member 7B
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the plasma membrane, cytosol & cell junctions.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (approved), Cell Junctions (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA016873
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the plasma membrane, cytosol & cell junctions.

Main location

Plasma membrane (approved), Cell Junctions (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA016873	A-431	Plasma membrane
			Cell Junctions
			Cytosol
	HPA016873	U-2 OS	Plasma membrane
	HPA016873	U-2 OS	Cytosol
	HPA016873	U-251 MG	Nucleoplasm
			Cell Junctions
			Cytosol

GENE INFORMATION
Gene name	DHRS7B (HGNC Symbol)
Synonyms	CGI-93, DKFZp566O084, MGC8916, SDR32C1
Description	Dehydrogenase/reductase (SDR family) member 7B (HGNC Symbol)
Entrez gene summary	This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]
Chromosome	17
Cytoband	p11.2
Chromosome location (bp)	21123364 - 21193265
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000109016 (version 83.38)
Entrez gene	25979
UniProt	Q6IAN0 (UniProt - Evidence at protein level)
neXtProt	NX_Q6IAN0
Antibodypedia	DHRS7B antibodies

PROTEIN BROWSER

DHRS7B-001	DHRS7B-002	DHRS7B-009	DHRS7B-010	DHRS7B-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DHRS7B-001 ENSP00000378887 ENST00000395511	Q6IAN0 [Direct mapping] Dehydrogenase/reductase SDR family member 7B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005789 [endoplasmic reticulum membrane] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	325 aa 35.1 kDa	No	2
DHRS7B-002 ENSP00000468585 ENST00000579303	A0A0C4DGQ8 [Direct mapping] Dehydrogenase/reductase SDR family member 7B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	310 aa 33.5 kDa	No	2
DHRS7B-009 ENSP00000463588 ENST00000581463	J3QLJ8 [Direct mapping] Dehydrogenase/reductase SDR family member 7B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	107 aa 11.9 kDa	No	0
DHRS7B-010 ENSP00000462139 ENST00000583388	J3KRS1 [Direct mapping] Dehydrogenase/reductase SDR family member 7B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	125 aa 13.6 kDa	No	1
DHRS7B-011 ENSP00000463221 ENST00000582161	J3QKT1 [Direct mapping] Dehydrogenase/reductase SDR family member 7B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	126 aa 13.4 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.