Expression of PRPF40B in cancer - Summary - The Human Protein Atlas

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PRPF40B

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

PRP40 homolog, pre-mRNA processing factor B

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA038426	HPA038599

GENE INFORMATION
Gene name	PRPF40B (HGNC Symbol)
Synonyms	HYPC
Description	PRP40 homolog, pre-mRNA processing factor B (HGNC Symbol)
Entrez gene summary	This gene encodes a WW-domain containing protein similar to yeast splicing factor PRP40. This protein has been shown to interact with Huntingtin and methyl CpG binding protein 2 (MeCP2). Alternative splicing results in different transcript variants. [provided by RefSeq, Aug 2014]
Chromosome	12
Cytoband	q13.12
Chromosome location (bp)	49568218 - 49644666
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000110844 (version 83.38)
Entrez gene	25766
UniProt	Q6NWY9 (UniProt - Evidence at protein level)
neXtProt	NX_Q6NWY9
Antibodypedia	PRPF40B antibodies

PROTEIN BROWSER

PRPF40B-001	PRPF40B-002	PRPF40B-003	PRPF40B-019

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRPF40B-001 ENSP00000369634 ENST00000380281	Q6NWY9 [Direct mapping] Pre-mRNA-processing factor 40 homolog B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000398 [mRNA splicing, via spliceosome] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005685 [U1 snRNP] GO:0016607 [nuclear speck] GO:0071004 [U2-type prespliceosome] Show all	871 aa 99.4 kDa	No	0
PRPF40B-002 ENSP00000261897 ENST00000261897	Q6NWY9 [Direct mapping] Pre-mRNA-processing factor 40 homolog B Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000398 [mRNA splicing, via spliceosome] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005685 [U1 snRNP] GO:0016607 [nuclear speck] GO:0071004 [U2-type prespliceosome] Show all	858 aa 97.8 kDa	No	0
PRPF40B-003 ENSP00000449569 ENST00000551063		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		6 aa 0.7 kDa	No	0
PRPF40B-019 ENSP00000448073 ENST00000548825	F8VU11 [Direct mapping] PRP40 pre-mRNA processing factor 40 homolog B (Yeast), isoform CRA_a; Pre-mRNA-processing factor 40 homolog B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	892 aa 101.4 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.