We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Several cases of endometrial cancers along with a few gliomas, breast, pancreatic and liver cancers displayed weak to moderate cytoplasmic immunoreactivity. Remaining cancer tissues were generally negative.
Cancer cells displayed moderate to strong cytoplasmic positivity. A majority of renal and urothelial cancers were weakly stained or negative.
GENE INFORMATION
Gene name
MDM1
Synonyms
Description
Mdm1 nuclear protein (HGNC Symbol)
Entrez gene summary
This gene encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
