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COPS7A

CANCER ATLAS

Gene description

 COP9 signalosome subunit 7A

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA026915

GENE INFORMATION

Gene name

 COPS7A (HGNC Symbol)

Synonyms

 CSN7A

Description

 COP9 signalosome subunit 7A (HGNC Symbol)

Entrez gene summary

 This gene encodes a component of the COP9 signalosome, an evolutionarily conserved multi-subunit protease that regulates the activity of the ubiquitin conjugation pathway. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Mar 2014]

Chromosome

 12

Cytoband

 p13.31

Chromosome location (bp)

 6723741 - 6731875

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000111652 (version 83.38)

Entrez gene

 50813

UniProt

 Q9UBW8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UBW8

Antibodypedia

 COPS7A antibodies

PROTEIN BROWSER
COPS7A-001
COPS7A-002
COPS7A-003
COPS7A-004
COPS7A-006
COPS7A-015
COPS7A-022
COPS7A-024
COPS7A-027
COPS7A-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
COPS7A-001
ENSP00000438115
ENST00000543155
Q9UBW8 [Direct mapping]
COP9 signalosome complex subunit 7a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000715 [nucleotide-excision repair, DNA damage recognition]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006281 [DNA repair]
GO:0006283 [transcription-coupled nucleotide-excision repair]
GO:0006289 [nucleotide-excision repair]
GO:0008180 [COP9 signalosome]
GO:0010388 [cullin deneddylation]
GO:0070911 [global genome nucleotide-excision repair]
Show all
 275 aa
30.3 kDa 		No 0
COPS7A-002
ENSP00000446039
ENST00000534947
Q9UBW8 [Direct mapping]
COP9 signalosome complex subunit 7a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000715 [nucleotide-excision repair, DNA damage recognition]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006281 [DNA repair]
GO:0006283 [transcription-coupled nucleotide-excision repair]
GO:0006289 [nucleotide-excision repair]
GO:0008180 [COP9 signalosome]
GO:0010388 [cullin deneddylation]
GO:0070911 [global genome nucleotide-excision repair]
Show all
 275 aa
30.3 kDa 		No 0
COPS7A-003
ENSP00000438363
ENST00000534877
Q9UBW8 [Direct mapping]
COP9 signalosome complex subunit 7a
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000715 [nucleotide-excision repair, DNA damage recognition]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006281 [DNA repair]
GO:0006283 [transcription-coupled nucleotide-excision repair]
GO:0006289 [nucleotide-excision repair]
GO:0008180 [COP9 signalosome]
GO:0010388 [cullin deneddylation]
GO:0070911 [global genome nucleotide-excision repair]
Show all
 275 aa
30.3 kDa 		No 0
COPS7A-004
ENSP00000441852
ENST00000539735
Q9UBW8 [Direct mapping]
COP9 signalosome complex subunit 7a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000715 [nucleotide-excision repair, DNA damage recognition]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006281 [DNA repair]
GO:0006283 [transcription-coupled nucleotide-excision repair]
GO:0006289 [nucleotide-excision repair]
GO:0008180 [COP9 signalosome]
GO:0010388 [cullin deneddylation]
GO:0070911 [global genome nucleotide-excision repair]
Show all
 275 aa
30.3 kDa 		No 0
COPS7A-006
ENSP00000229251
ENST00000229251
Q9UBW8 [Direct mapping]
COP9 signalosome complex subunit 7a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000715 [nucleotide-excision repair, DNA damage recognition]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006281 [DNA repair]
GO:0006283 [transcription-coupled nucleotide-excision repair]
GO:0006289 [nucleotide-excision repair]
GO:0008180 [COP9 signalosome]
GO:0010388 [cullin deneddylation]
GO:0070911 [global genome nucleotide-excision repair]
Show all
 275 aa
30.3 kDa 		No 0
COPS7A-015
ENSP00000439547
ENST00000538410
F5H248 [Direct mapping]
COP9 signalosome complex subunit 7a
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
Show all
 262 aa
29 kDa 		No 0
COPS7A-022
ENSP00000440683
ENST00000538753
F5GYF7 [Direct mapping]
COP9 signalosome complex subunit 7a
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
Show all
 213 aa
23.7 kDa 		No 0
COPS7A-024
ENSP00000439949
ENST00000544725
F5H4U8 [Direct mapping]
COP9 signalosome complex subunit 7a
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
Show all
 125 aa
13.7 kDa 		No 0
COPS7A-027
ENSP00000442613
ENST00000541866
F5H7C6 [Direct mapping]
COP9 signalosome complex subunit 7a
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
Show all
 192 aa
21.3 kDa 		No 0
COPS7A-201
ENSP00000487362
ENST00000626119
G3XAP1 [Direct mapping]
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis), isoform CRA_b; COP9 signalosome complex subunit 7a
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 62 aa
6.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.