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ACOT13

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GENERAL INFORMATION

Gene name

 ACOT13

Gene description

 Acyl-CoA thioesterase 13

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the cell junctions.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Cell Junctions (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA019881
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the cell junctions.

Main location

 Cell Junctions (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA019881 A-431 Cell Junctions
HPA019881 U-251 MG Nucleoplasm
Cell Junctions

GENE INFORMATION

Gene name

 ACOT13 (HGNC Symbol)

Synonyms

 HT012, THEM2

Description

 Acyl-CoA thioesterase 13 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2009]

Chromosome

 6

Cytoband

 p22.3

Chromosome location (bp)

 24667035 - 24705065

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000112304 (version 83.38)

Entrez gene

 55856

UniProt

 Q9NPJ3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NPJ3

Antibodypedia

 ACOT13 antibodies

PROTEIN BROWSER
ACOT13-001
ACOT13-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ACOT13-001
ENSP00000230048
ENST00000230048
Q9NPJ3 [Direct mapping]
Acyl-coenzyme A thioesterase 13 Acyl-coenzyme A thioesterase 13, N-terminally processed
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005634 [nucleus]
GO:0005739 [mitochondrion]
GO:0005819 [spindle]
GO:0005829 [cytosol]
GO:0019432 [triglyceride biosynthetic process]
GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0047617 [acyl-CoA hydrolase activity]
GO:0051289 [protein homotetramerization]
GO:0070062 [extracellular exosome]
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 140 aa
15 kDa 		No 0
ACOT13-201
ENSP00000445552
ENST00000537591
Q9NPJ3 [Direct mapping]
Acyl-coenzyme A thioesterase 13 Acyl-coenzyme A thioesterase 13, N-terminally processed
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005739 [mitochondrion]
GO:0005819 [spindle]
GO:0005829 [cytosol]
GO:0019432 [triglyceride biosynthetic process]
GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0047617 [acyl-CoA hydrolase activity]
GO:0051289 [protein homotetramerization]
GO:0070062 [extracellular exosome]
Show all
 117 aa
12.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.