Tissue expression of B3GAT2 - Summary - The Human Protein Atlas

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B3GAT2

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	B3GAT2
Gene description	Beta-1,3-glucuronyltransferase 2
Protein class	Enzymes Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (cerebral cortex)
GTEx:	Tissue enhanced (hypothalamus, hippocampus)
FANTOM5:	Group enriched (hippocampus, brain, caudate, cerebellum)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Antibody staining mainly not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA012059
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (cerebral cortex)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (hypothalamus, hippocampus)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (hippocampus, brain, caudate, cerebellum)

GENE INFORMATION
Gene name	B3GAT2 (HGNC Symbol)
Synonyms	GlcAT-S
Description	Beta-1,3-glucuronyltransferase 2 (HGNC Symbol)
Entrez gene summary	The product of this gene is a transmembrane protein belonging to the glucuronyltransferase family, and catalyzes the transfer of a beta-1,3 linked glucuronic acid to a terminal galactose in different glycoproteins or glycolipids containing a Gal-beta-1-4GlcNAc or Gal-beta-1-3GlcNAc residue. The encoded protein is involved in the synthesis of the human natural killer-1 (HNK-1) carbohydrate epitope, a sulfated trisaccharide implicated in cellular migration and adhesion in the nervous system. [provided by RefSeq, Jul 2008]
Chromosome	6
Cytoband	q13
Chromosome location (bp)	70856679 - 70957038
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000112309 (version 83.38)
Entrez gene	135152
UniProt	Q9NPZ5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NPZ5
Antibodypedia	B3GAT2 antibodies

PROTEIN BROWSER

B3GAT2-001	B3GAT2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
B3GAT2-001 ENSP00000230053 ENST00000230053	Q9NPZ5 [Direct mapping] Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0000139 [Golgi membrane] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0015018 [galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0030204 [chondroitin sulfate metabolic process] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0050650 [chondroitin sulfate proteoglycan biosynthetic process] Show all	323 aa 36.9 kDa	No	1
B3GAT2-201 ENSP00000481320 ENST00000615536	A0A087WXU9 [Direct mapping] Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0008152 [metabolic process] GO:0015018 [galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	251 aa 28.6 kDa	No	1

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.