Cell atlas - SLC16A10 - The Human Protein Atlas

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SLC16A10

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cell Junctions
	Vesicles

Human cell
	Plasma Membrane
	Vesicles

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GENERAL INFORMATION
Gene name	SLC16A10
Gene description	Solute carrier family 16 (aromatic amino acid transporter), member 10
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cell junctions & vesicles.
RNA cell category	Cell line enhanced (RPMI-8226, HEK 293)
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (approved), Cell Junctions (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA016860
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (RPMI-8226, HEK 293) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cell junctions & vesicles.

Main location

Vesicles (approved), Cell Junctions (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA016860	CACO-2	Vesicles
	HPA016860	CACO-2	Cell Junctions
	HPA016860	U-2 OS	No staining

GENE INFORMATION
Gene name	SLC16A10 (HGNC Symbol)
Synonyms	MCT10, TAT1
Description	Solute carrier family 16 (aromatic amino acid transporter), member 10 (HGNC Symbol)
Entrez gene summary	SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic amino acids across the plasma membrane.[supplied by OMIM, Apr 2004]
Chromosome	6
Cytoband	q21
Chromosome location (bp)	111087503 - 111231194
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000112394 (version 83.38)
Entrez gene	117247
UniProt	Q8TF71 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TF71
Antibodypedia	SLC16A10 antibodies

PROTEIN BROWSER

SLC16A10-001	SLC16A10-002	SLC16A10-003	SLC16A10-004	SLC16A10-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC16A10-001 ENSP00000357844 ENST00000368851	Q8TF71 [Direct mapping] Monocarboxylate transporter 10 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0006865 [amino acid transport] GO:0015173 [aromatic amino acid transmembrane transporter activity] GO:0015349 [thyroid hormone transmembrane transporter activity] GO:0015801 [aromatic amino acid transport] GO:0016021 [integral component of membrane] GO:0016323 [basolateral plasma membrane] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] GO:0070327 [thyroid hormone transport] Show all	515 aa 55.5 kDa	No	>9
SLC16A10-002 ENSP00000357843 ENST00000368850	Q9P1I2 [Direct mapping] Monocarboxylate transporter 10; PRO0813 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] Show all	201 aa 22 kDa	No	5
SLC16A10-003 ENSP00000399601 ENST00000419619	H0Y5M8 [Direct mapping] Monocarboxylate transporter 10 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005887 [integral component of plasma membrane] GO:0015173 [aromatic amino acid transmembrane transporter activity] GO:0015349 [thyroid hormone transmembrane transporter activity] GO:0015801 [aromatic amino acid transport] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] GO:0070327 [thyroid hormone transport] Show all	211 aa 23 kDa	No	6
SLC16A10-004 ENSP00000387501 ENST00000439288	H0Y3W8 [Direct mapping] Monocarboxylate transporter 10 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005887 [integral component of plasma membrane] GO:0015173 [aromatic amino acid transmembrane transporter activity] GO:0015349 [thyroid hormone transmembrane transporter activity] GO:0015801 [aromatic amino acid transport] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] GO:0070327 [thyroid hormone transport] Show all	206 aa 22.4 kDa	No	6
SLC16A10-201 ENSP00000483868 ENST00000612036	A0A087X138 [Direct mapping] Monocarboxylate transporter 10 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005887 [integral component of plasma membrane] GO:0015173 [aromatic amino acid transmembrane transporter activity] GO:0015349 [thyroid hormone transmembrane transporter activity] GO:0015801 [aromatic amino acid transport] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] GO:0070327 [thyroid hormone transport] Show all	326 aa 34.8 kDa	No	6

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.