Expression of C7 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Complement component 7

Protein class

Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA001465

GENE INFORMATION
Gene name	C7
Synonyms
Description	Complement component 7 (HGNC Symbol)
Entrez gene summary	C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008]
Chromosome	5
Cytoband	p13.1
Chromosome location (bp)	40909252 - 40982939
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000112936 (version 83.38)
Entrez gene	730
UniProt	P10643 (UniProt - Evidence at protein level)
neXtProt	NX_P10643
Antibodypedia	C7 antibodies

PROTEIN BROWSER

C7-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C7-001 ENSP00000322061 ENST00000313164	P10643 [Direct mapping] Complement component C7 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0005579 [membrane attack complex] GO:0006956 [complement activation] GO:0006957 [complement activation, alternative pathway] GO:0006958 [complement activation, classical pathway] GO:0019835 [cytolysis] GO:0030449 [regulation of complement activation] GO:0045087 [innate immune response] GO:0070062 [extracellular exosome] Show all	843 aa 93.5 kDa	Yes	0