Fields »
ABOUT
HELP
BLOG
GOLPH3

GENERAL INFORMATION

Gene name

 GOLPH3

Gene description

 Golgi phosphoprotein 3 (coat-protein)

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Golgi-like cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 2 antibodies.
HPA044564 , HPA055841
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Stomach

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 GOLPH3 (HGNC Symbol)

Synonyms

 GOPP1, GPP34, MIDAS, Vps74

Description

 Golgi phosphoprotein 3 (coat-protein) (HGNC Symbol)

Entrez gene summary

 The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a peripheral membrane protein of the Golgi stack and may have a regulatory role in Golgi trafficking. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

 5

Cytoband

 p13.3

Chromosome location (bp)

 32124704 - 32174350

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000113384 (version 83.38)

Entrez gene

 64083

UniProt

 Q9H4A6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H4A6

Antibodypedia

 GOLPH3 antibodies

PROTEIN BROWSER
GOLPH3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GOLPH3-001
ENSP00000265070
ENST00000265070
Q9H4A6 [Direct mapping]
Golgi phosphoprotein 3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005739 [mitochondrion]
GO:0005758 [mitochondrial intermembrane space]
GO:0005768 [endosome]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0007030 [Golgi organization]
GO:0008283 [cell proliferation]
GO:0009101 [glycoprotein biosynthetic process]
GO:0009306 [protein secretion]
GO:0010467 [gene expression]
GO:0010821 [regulation of mitochondrion organization]
GO:0016477 [cell migration]
GO:0019899 [enzyme binding]
GO:0030032 [lamellipodium assembly]
GO:0031985 [Golgi cisterna]
GO:0032008 [positive regulation of TOR signaling]
GO:0032580 [Golgi cisterna membrane]
GO:0043001 [Golgi to plasma membrane protein transport]
GO:0043066 [negative regulation of apoptotic process]
GO:0045053 [protein retention in Golgi apparatus]
GO:0048194 [Golgi vesicle budding]
GO:0050714 [positive regulation of protein secretion]
GO:0050901 [leukocyte tethering or rolling]
GO:0060352 [cell adhesion molecule production]
GO:0070273 [phosphatidylinositol-4-phosphate binding]
GO:0090161 [Golgi ribbon formation]
GO:0090164 [asymmetric Golgi ribbon formation]
Show all
 298 aa
33.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.