Fields »
ABOUT
HELP
BLOG
NUP155

CANCER ATLAS

Gene description

 Nucleoporin 155kDa

Protein class

 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA037775

GENE INFORMATION

Gene name

 NUP155 (HGNC Symbol)

Synonyms

 KIAA0791, N155

Description

 Nucleoporin 155kDa (HGNC Symbol)

Entrez gene summary

 Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013]

Chromosome

 5

Cytoband

 p13.2

Chromosome location (bp)

 37288137 - 37371181

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000113569 (version 83.38)

Entrez gene

 9631

UniProt

 O75694 (UniProt - Evidence at protein level)

neXtProt

 NX_O75694

Antibodypedia

 NUP155 antibodies

PROTEIN BROWSER
NUP155-001
NUP155-003
NUP155-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NUP155-001
ENSP00000231498
ENST00000231498
O75694 [Direct mapping]
Nuclear pore complex protein Nup155
A0A024R071 [Target identity:100%; Query identity:100%]
Nucleoporin 155kDa, isoform CRA_a
Show all
Transporters
   Transporter channels and pores
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000278 [mitotic cell cycle]
GO:0005215 [transporter activity]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005975 [carbohydrate metabolic process]
GO:0006406 [mRNA export from nucleus]
GO:0006606 [protein import into nucleus]
GO:0006998 [nuclear envelope organization]
GO:0007077 [mitotic nuclear envelope disassembly]
GO:0008033 [tRNA processing]
GO:0008645 [hexose transport]
GO:0010467 [gene expression]
GO:0010827 [regulation of glucose transport]
GO:0015758 [glucose transport]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016925 [protein sumoylation]
GO:0017056 [structural constituent of nuclear pore]
GO:0019048 [modulation by virus of host morphology or physiology]
GO:0019054 [modulation by virus of host process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0031047 [gene silencing by RNA]
GO:0031965 [nuclear membrane]
GO:0034605 [cellular response to heat]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0055085 [transmembrane transport]
GO:0086014 [atrial cardiac muscle cell action potential]
GO:1900034 [regulation of cellular response to heat]
Show all
 1391 aa
155.2 kDa 		Yes 0
NUP155-003
ENSP00000422019
ENST00000513532
E9PF10 [Direct mapping]
Nuclear pore complex protein Nup155
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005643 [nuclear pore]
GO:0006913 [nucleocytoplasmic transport]
GO:0017056 [structural constituent of nuclear pore]
Show all
 1327 aa
148.1 kDa 		Yes 0
NUP155-004
ENSP00000371265
ENST00000381843
O75694 [Direct mapping]
Nuclear pore complex protein Nup155
Show all
Transporters
   Transporter channels and pores
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000278 [mitotic cell cycle]
GO:0005215 [transporter activity]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005975 [carbohydrate metabolic process]
GO:0006998 [nuclear envelope organization]
GO:0007077 [mitotic nuclear envelope disassembly]
GO:0008033 [tRNA processing]
GO:0008645 [hexose transport]
GO:0010467 [gene expression]
GO:0010827 [regulation of glucose transport]
GO:0015758 [glucose transport]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016925 [protein sumoylation]
GO:0017056 [structural constituent of nuclear pore]
GO:0019048 [modulation by virus of host morphology or physiology]
GO:0019054 [modulation by virus of host process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0031047 [gene silencing by RNA]
GO:0031965 [nuclear membrane]
GO:0034605 [cellular response to heat]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0055085 [transmembrane transport]
GO:1900034 [regulation of cellular response to heat]
Show all
 1332 aa
149 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.