Expression of NIT2 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Nitrilase family, member 2

Protein class

Enzymes, Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA036999

GENE INFORMATION
Gene name	NIT2
Synonyms
Description	Nitrilase family, member 2 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q12.2
Chromosome location (bp)	100334701 - 100361635
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000114021 (version 83.38)
Entrez gene	56954
UniProt	Q9NQR4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NQR4
Antibodypedia	NIT2 antibodies

PROTEIN BROWSER

NIT2-001	NIT2-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NIT2-001 ENSP00000377696 ENST00000394140	Q9NQR4 [Direct mapping] Omega-amidase NIT2 V9HW91 [Target identity:100%; Query identity:100%] Epididymis secretory sperm binding protein Li 8a Show all	Enzymes ENZYME proteins Hydrolases Phobius predicted secreted proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005813 [centrosome] GO:0006107 [oxaloacetate metabolic process] GO:0006528 [asparagine metabolic process] GO:0006541 [glutamine metabolic process] GO:0006807 [nitrogen compound metabolic process] GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds] GO:0050152 [omega-amidase activity] GO:0070062 [extracellular exosome] Show all	276 aa 30.6 kDa	No	0
NIT2-002 ENSP00000419189 ENST00000497785	H7C579 [Direct mapping] Omega-amidase NIT2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006807 [nitrogen compound metabolic process] GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds] Show all	266 aa 28.7 kDa	No	0