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NIT2

GENERAL INFORMATION

Gene name

 NIT2

Gene description

 Nitrilase family, member 2

Protein class

 Enzymes
Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Presumed off target binding observed and disregarded. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA036999
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 NIT2

Synonyms

Description

 Nitrilase family, member 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 3

Cytoband

 q12.2

Chromosome location (bp)

 100334701 - 100361635

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000114021 (version 83.38)

Entrez gene

 56954

UniProt

 Q9NQR4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NQR4

Antibodypedia

 NIT2 antibodies

PROTEIN BROWSER
NIT2-001
NIT2-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NIT2-001
ENSP00000377696
ENST00000394140
Q9NQR4 [Direct mapping]
Omega-amidase NIT2
V9HW91 [Target identity:100%; Query identity:100%]
Epididymis secretory sperm binding protein Li 8a
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Enzymes
   ENZYME proteins
   Hydrolases
   Phobius predicted secreted proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005813 [centrosome]
GO:0006107 [oxaloacetate metabolic process]
GO:0006528 [asparagine metabolic process]
GO:0006541 [glutamine metabolic process]
GO:0006807 [nitrogen compound metabolic process]
GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds]
GO:0050152 [omega-amidase activity]
GO:0070062 [extracellular exosome]
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 276 aa
30.6 kDa 		No 0
NIT2-002
ENSP00000419189
ENST00000497785
H7C579 [Direct mapping]
Omega-amidase NIT2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006807 [nitrogen compound metabolic process]
GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds]
Show all
 266 aa
28.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.