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Malignant tissues generally displayed moderate cytoplasmic and nuclear positivity. Strong staining was observed in several malignant lymphomas, lung, colorectal and breast cancers. Most cases of malignant gliomas were weakly stained or negative.
Malignant tissues displayed moderate cytoplasmic and/or nuclear positivity. Strong staining was observed in several cases of malignant carcinoids, colorectal, breast, prostate and testicular cancers.
Q8WTW4 [Direct mapping] Nitrogen permease regulator 2-like protein
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THUMBUP predicted membrane proteins Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0004672 [protein kinase activity] GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0006468 [protein phosphorylation] GO:0032007 [negative regulation of TOR signaling] GO:0033673 [negative regulation of kinase activity] GO:0034198 [cellular response to amino acid starvation] GO:0043547 [positive regulation of GTPase activity] GO:1990130 [Iml1 complex]