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CSPG5

CANCER ATLAS

Gene description

 Chondroitin sulfate proteoglycan 5 (neuroglycan C)

Protein class

 Predicted membrane proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Glioma

STAINING SUMMARY
HPA071779

GENE INFORMATION

Gene name

 CSPG5 (HGNC Symbol)

Synonyms

 NGC

Description

 Chondroitin sulfate proteoglycan 5 (neuroglycan C) (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a proteoglycan that may function as a neural growth and differentiation factor. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

Chromosome

 3

Cytoband

 p21.31

Chromosome location (bp)

 47562239 - 47580792

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000114646 (version 83.38)

Entrez gene

 10675

UniProt

 O95196 (UniProt - Evidence at protein level)

neXtProt

 NX_O95196

Antibodypedia

 CSPG5 antibodies

PROTEIN BROWSER
CSPG5-001
CSPG5-002
CSPG5-003
CSPG5-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CSPG5-001
ENSP00000373244
ENST00000383738
O95196 [Direct mapping]
Chondroitin sulfate proteoglycan 5
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0002230 [positive regulation of defense response to virus by host]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005796 [Golgi lumen]
GO:0005887 [integral component of plasma membrane]
GO:0005975 [carbohydrate metabolic process]
GO:0007399 [nervous system development]
GO:0008083 [growth factor activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0030154 [cell differentiation]
GO:0030203 [glycosaminoglycan metabolic process]
GO:0030204 [chondroitin sulfate metabolic process]
GO:0030206 [chondroitin sulfate biosynthetic process]
GO:0030207 [chondroitin sulfate catabolic process]
GO:0030208 [dermatan sulfate biosynthetic process]
GO:0030660 [Golgi-associated vesicle membrane]
GO:0040008 [regulation of growth]
GO:0043202 [lysosomal lumen]
GO:0044281 [small molecule metabolic process]
GO:0046907 [intracellular transport]
GO:0050804 [modulation of synaptic transmission]
GO:0098779 [mitophagy in response to mitochondrial depolarization]
Show all
 566 aa
60 kDa 		Yes 1
CSPG5-002
ENSP00000264723
ENST00000264723
O95196 [Direct mapping]
Chondroitin sulfate proteoglycan 5
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0002230 [positive regulation of defense response to virus by host]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005796 [Golgi lumen]
GO:0005887 [integral component of plasma membrane]
GO:0005975 [carbohydrate metabolic process]
GO:0007399 [nervous system development]
GO:0008083 [growth factor activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0030154 [cell differentiation]
GO:0030203 [glycosaminoglycan metabolic process]
GO:0030204 [chondroitin sulfate metabolic process]
GO:0030206 [chondroitin sulfate biosynthetic process]
GO:0030207 [chondroitin sulfate catabolic process]
GO:0030208 [dermatan sulfate biosynthetic process]
GO:0030660 [Golgi-associated vesicle membrane]
GO:0040008 [regulation of growth]
GO:0043202 [lysosomal lumen]
GO:0044281 [small molecule metabolic process]
GO:0046907 [intracellular transport]
GO:0098779 [mitophagy in response to mitochondrial depolarization]
Show all
 539 aa
57 kDa 		Yes 1
CSPG5-003
ENSP00000392096
ENST00000456150
O95196 [Direct mapping]
Chondroitin sulfate proteoglycan 5
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0002230 [positive regulation of defense response to virus by host]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005796 [Golgi lumen]
GO:0005887 [integral component of plasma membrane]
GO:0005975 [carbohydrate metabolic process]
GO:0007399 [nervous system development]
GO:0008083 [growth factor activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0030154 [cell differentiation]
GO:0030203 [glycosaminoglycan metabolic process]
GO:0030204 [chondroitin sulfate metabolic process]
GO:0030206 [chondroitin sulfate biosynthetic process]
GO:0030207 [chondroitin sulfate catabolic process]
GO:0030208 [dermatan sulfate biosynthetic process]
GO:0030660 [Golgi-associated vesicle membrane]
GO:0040008 [regulation of growth]
GO:0043202 [lysosomal lumen]
GO:0044281 [small molecule metabolic process]
GO:0046907 [intracellular transport]
GO:0098779 [mitophagy in response to mitochondrial depolarization]
Show all
 401 aa
43.6 kDa 		No 1
CSPG5-201
ENSP00000478923
ENST00000610462
A0A087WUT8 [Direct mapping]
Chondroitin sulfate proteoglycan 5
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0016021 [integral component of membrane]
Show all
 477 aa
50.2 kDa 		Yes 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.