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FOXP1

GENERAL INFORMATION

Gene name

 FOXP1

Gene description

 Forkhead box P1

Protein class

 Cancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 16
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear expression in most cells.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA003876 , CAB011501
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 FOXP1 (HGNC Symbol)

Synonyms

 12CC4, hFKH1B, HSPC215, QRF1

Description

 Forkhead box P1 (HGNC Symbol)

Entrez gene summary

 This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

 3

Cytoband

 p13

Chromosome location (bp)

 70954693 - 71583989

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000114861 (version 83.38)

Entrez gene

 27086

UniProt

 Q9H334 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H334

Antibodypedia

 FOXP1 antibodies

PROTEIN BROWSER
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FOXP1-001
FOXP1-002
FOXP1-004
FOXP1-005
FOXP1-006
FOXP1-009
FOXP1-011
FOXP1-012
FOXP1-014
FOXP1-019
FOXP1-020
FOXP1-021
FOXP1-023
FOXP1-024
FOXP1-201
FOXP1-202
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FOXP1-001
ENSP00000318902
ENST00000318789
Q9H334 [Direct mapping]
Forkhead box protein P1
Q548T7 [Target identity:100%; Query identity:100%]
12CC4; Forkhead box P1, isoform CRA_a
Show all
Predicted intracellular proteins
Plasma proteins
Transcription factors
   Helix-turn-helix domains
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0002903 [negative regulation of B cell apoptotic process]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0010595 [positive regulation of endothelial cell migration]
GO:0030316 [osteoclast differentiation]
GO:0032496 [response to lipopolysaccharide]
GO:0032680 [regulation of tumor necrosis factor production]
GO:0035926 [chemokine (C-C motif) ligand 2 secretion]
GO:0036035 [osteoclast development]
GO:0042116 [macrophage activation]
GO:0042117 [monocyte activation]
GO:0042118 [endothelial cell activation]
GO:0043565 [sequence-specific DNA binding]
GO:0045655 [regulation of monocyte differentiation]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:0048661 [positive regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050706 [regulation of interleukin-1 beta secretion]
GO:0050727 [regulation of inflammatory response]
GO:0060766 [negative regulation of androgen receptor signaling pathway]
GO:0061470 [T follicular helper cell differentiation]
GO:0072619 [interleukin-21 secretion]
GO:1900424 [regulation of defense response to bacterium]
GO:1901256 [regulation of macrophage colony-stimulating factor production]
GO:1901509 [regulation of endothelial tube morphogenesis]
GO:2001182 [regulation of interleukin-12 secretion]
Show all
 677 aa
75.3 kDa 		No 0
FOXP1-002
ENSP00000418524
ENST00000493089
Q9H334 [Direct mapping]
Forkhead box protein P1
Show all
Predicted intracellular proteins
Plasma proteins
Transcription factors
   Helix-turn-helix domains
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0002903 [negative regulation of B cell apoptotic process]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0010595 [positive regulation of endothelial cell migration]
GO:0030316 [osteoclast differentiation]
GO:0032496 [response to lipopolysaccharide]
GO:0032680 [regulation of tumor necrosis factor production]
GO:0035926 [chemokine (C-C motif) ligand 2 secretion]
GO:0036035 [osteoclast development]
GO:0042116 [macrophage activation]
GO:0042117 [monocyte activation]
GO:0042118 [endothelial cell activation]
GO:0043565 [sequence-specific DNA binding]
GO:0045655 [regulation of monocyte differentiation]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:0048661 [positive regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050706 [regulation of interleukin-1 beta secretion]
GO:0050727 [regulation of inflammatory response]
GO:0060766 [negative regulation of androgen receptor signaling pathway]
GO:0061470 [T follicular helper cell differentiation]
GO:0072619 [interleukin-21 secretion]
GO:1900424 [regulation of defense response to bacterium]
GO:1901256 [regulation of macrophage colony-stimulating factor production]
GO:1901509 [regulation of endothelial tube morphogenesis]
GO:2001182 [regulation of interleukin-12 secretion]
Show all
 676 aa
75.2 kDa 		No 0
FOXP1-004
ENSP00000419393
ENST00000475937
Q9H334 [Direct mapping]
Forkhead box protein P1
Q548T7 [Target identity:100%; Query identity:100%]
12CC4; Forkhead box P1, isoform CRA_a
Show all
Predicted intracellular proteins
Plasma proteins
Transcription factors
   Helix-turn-helix domains
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0002903 [negative regulation of B cell apoptotic process]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0010595 [positive regulation of endothelial cell migration]
GO:0030316 [osteoclast differentiation]
GO:0032496 [response to lipopolysaccharide]
GO:0032680 [regulation of tumor necrosis factor production]
GO:0035926 [chemokine (C-C motif) ligand 2 secretion]
GO:0036035 [osteoclast development]
GO:0042116 [macrophage activation]
GO:0042117 [monocyte activation]
GO:0042118 [endothelial cell activation]
GO:0043565 [sequence-specific DNA binding]
GO:0045655 [regulation of monocyte differentiation]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:0048661 [positive regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050706 [regulation of interleukin-1 beta secretion]
GO:0050727 [regulation of inflammatory response]
GO:0060766 [negative regulation of androgen receptor signaling pathway]
GO:0061470 [T follicular helper cell differentiation]
GO:0072619 [interleukin-21 secretion]
GO:1900424 [regulation of defense response to bacterium]
GO:1901256 [regulation of macrophage colony-stimulating factor production]
GO:1901509 [regulation of endothelial tube morphogenesis]
GO:2001182 [regulation of interleukin-12 secretion]
Show all
 677 aa
75.3 kDa 		No 0
FOXP1-005
ENSP00000417857
ENST00000484350
Q9H334 [Direct mapping]
Forkhead box protein P1
Show all
Predicted intracellular proteins
Plasma proteins
Transcription factors
   Helix-turn-helix domains
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0002903 [negative regulation of B cell apoptotic process]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0010595 [positive regulation of endothelial cell migration]
GO:0030316 [osteoclast differentiation]
GO:0032496 [response to lipopolysaccharide]
GO:0032680 [regulation of tumor necrosis factor production]
GO:0035926 [chemokine (C-C motif) ligand 2 secretion]
GO:0036035 [osteoclast development]
GO:0042116 [macrophage activation]
GO:0042117 [monocyte activation]
GO:0042118 [endothelial cell activation]
GO:0043565 [sequence-specific DNA binding]
GO:0045655 [regulation of monocyte differentiation]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:0048661 [positive regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050706 [regulation of interleukin-1 beta secretion]
GO:0050727 [regulation of inflammatory response]
GO:0060766 [negative regulation of androgen receptor signaling pathway]
GO:0061470 [T follicular helper cell differentiation]
GO:0072619 [interleukin-21 secretion]
GO:1900424 [regulation of defense response to bacterium]
GO:1901256 [regulation of macrophage colony-stimulating factor production]
GO:1901509 [regulation of endothelial tube morphogenesis]
GO:2001182 [regulation of interleukin-12 secretion]
Show all
 601 aa
66.4 kDa 		No 0
FOXP1-006
ENSP00000418102
ENST00000498215
Q9H334 [Direct mapping]
Forkhead box protein P1
Q548T7 [Target identity:100%; Query identity:100%]
12CC4; Forkhead box P1, isoform CRA_a
Show all
Predicted intracellular proteins
Plasma proteins
Transcription factors
   Helix-turn-helix domains
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0002903 [negative regulation of B cell apoptotic process]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0010595 [positive regulation of endothelial cell migration]
GO:0030316 [osteoclast differentiation]
GO:0032496 [response to lipopolysaccharide]
GO:0032680 [regulation of tumor necrosis factor production]
GO:0035926 [chemokine (C-C motif) ligand 2 secretion]
GO:0036035 [osteoclast development]
GO:0042116 [macrophage activation]
GO:0042117 [monocyte activation]
GO:0042118 [endothelial cell activation]
GO:0043565 [sequence-specific DNA binding]
GO:0045655 [regulation of monocyte differentiation]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:0048661 [positive regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050706 [regulation of interleukin-1 beta secretion]
GO:0050727 [regulation of inflammatory response]
GO:0060766 [negative regulation of androgen receptor signaling pathway]
GO:0061470 [T follicular helper cell differentiation]
GO:0072619 [interleukin-21 secretion]
GO:1900424 [regulation of defense response to bacterium]
GO:1901256 [regulation of macrophage colony-stimulating factor production]
GO:1901509 [regulation of endothelial tube morphogenesis]
GO:2001182 [regulation of interleukin-12 secretion]
Show all
 677 aa
75.3 kDa 		No 0
FOXP1-009
ENSP00000418225
ENST00000497355
H0Y882 [Direct mapping]
Forkhead box protein P1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0043565 [sequence-specific DNA binding]
Show all
 573 aa
64 kDa 		No 0
FOXP1-011
ENSP00000420736
ENST00000491238
E9PFD3 [Direct mapping]
Forkhead box protein P1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0043565 [sequence-specific DNA binding]
Show all
 679 aa
76.3 kDa 		No 0
FOXP1-012
ENSP00000418883
ENST00000468577
C9J0F0 [Direct mapping]
Forkhead box protein P1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0043565 [sequence-specific DNA binding]
Show all
 613 aa
68.1 kDa 		No 0
FOXP1-014
ENSP00000318721
ENST00000318779
Q9H334 [Direct mapping]
Forkhead box protein P1
Show all
Predicted intracellular proteins
Plasma proteins
Transcription factors
   Helix-turn-helix domains
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0002903 [negative regulation of B cell apoptotic process]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0010595 [positive regulation of endothelial cell migration]
GO:0030316 [osteoclast differentiation]
GO:0032496 [response to lipopolysaccharide]
GO:0032680 [regulation of tumor necrosis factor production]
GO:0035926 [chemokine (C-C motif) ligand 2 secretion]
GO:0036035 [osteoclast development]
GO:0042116 [macrophage activation]
GO:0042117 [monocyte activation]
GO:0042118 [endothelial cell activation]
GO:0043565 [sequence-specific DNA binding]
GO:0045655 [regulation of monocyte differentiation]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:0048661 [positive regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050706 [regulation of interleukin-1 beta secretion]
GO:0050727 [regulation of inflammatory response]
GO:0060766 [negative regulation of androgen receptor signaling pathway]
GO:0061470 [T follicular helper cell differentiation]
GO:0072619 [interleukin-21 secretion]
GO:1900424 [regulation of defense response to bacterium]
GO:1901256 [regulation of macrophage colony-stimulating factor production]
GO:1901509 [regulation of endothelial tube morphogenesis]
GO:2001182 [regulation of interleukin-12 secretion]
Show all
 114 aa
12.3 kDa 		No 0
FOXP1-019
ENSP00000418784
ENST00000497553
C9IYY1 [Direct mapping]
Forkhead box protein P1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
Show all
 123 aa
14.3 kDa 		No 0
FOXP1-020
ENSP00000484963
ENST00000472382
A0A087X2G3 [Direct mapping]
Forkhead box protein P1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
Show all
 203 aa
23 kDa 		No 0
FOXP1-021
ENSP00000417941
ENST00000485326
C9J5T4 [Direct mapping]
Forkhead box protein P1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0005654 [nucleoplasm]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
Show all
 224 aa
25.4 kDa 		No 0
FOXP1-023
ENSP00000479663
ENST00000610810
A0A087WVT2 [Direct mapping]
Forkhead box protein P1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
Show all
 117 aa
12.6 kDa 		No 0
FOXP1-024
ENSP00000477918
ENST00000622151
Q9H334 [Direct mapping]
Forkhead box protein P1
Show all
Predicted intracellular proteins
Plasma proteins
Transcription factors
   Helix-turn-helix domains
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0002903 [negative regulation of B cell apoptotic process]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0010595 [positive regulation of endothelial cell migration]
GO:0030316 [osteoclast differentiation]
GO:0032496 [response to lipopolysaccharide]
GO:0032680 [regulation of tumor necrosis factor production]
GO:0035926 [chemokine (C-C motif) ligand 2 secretion]
GO:0036035 [osteoclast development]
GO:0042116 [macrophage activation]
GO:0042117 [monocyte activation]
GO:0042118 [endothelial cell activation]
GO:0043565 [sequence-specific DNA binding]
GO:0045655 [regulation of monocyte differentiation]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:0048661 [positive regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050706 [regulation of interleukin-1 beta secretion]
GO:0050727 [regulation of inflammatory response]
GO:0060766 [negative regulation of androgen receptor signaling pathway]
GO:0061470 [T follicular helper cell differentiation]
GO:0072619 [interleukin-21 secretion]
GO:1900424 [regulation of defense response to bacterium]
GO:1901256 [regulation of macrophage colony-stimulating factor production]
GO:1901509 [regulation of endothelial tube morphogenesis]
GO:2001182 [regulation of interleukin-12 secretion]
Show all
 114 aa
12.3 kDa 		No 0
FOXP1-201
ENSP00000482847
ENST00000614176
A0A0B4J2F3 [Direct mapping]
Forkhead box protein P1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0043565 [sequence-specific DNA binding]
Show all
 577 aa
64.8 kDa 		No 0
FOXP1-202
ENSP00000484803
ENST00000615603
A0A087X299 [Direct mapping]
Forkhead box protein P1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0043565 [sequence-specific DNA binding]
Show all
 693 aa
77.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.