Expression of USP34 in cancer - Summary

CANCER ATLAS

Gene description

Ubiquitin specific peptidase 34

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA025815

GENE INFORMATION
Gene name	USP34 (HGNC Symbol)
Synonyms	KIAA0570, KIAA0729
Description	Ubiquitin specific peptidase 34 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p15
Chromosome location (bp)	61187463 - 61470769
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000115464 (version 83.38)
Entrez gene	9736
UniProt	Q70CQ2 (UniProt - Evidence at protein level)
neXtProt	NX_Q70CQ2
Antibodypedia	USP34 antibodies

PROTEIN BROWSER

USP34-001	USP34-002	USP34-005	USP34-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
USP34-001 ENSP00000381577 ENST00000398571	Q70CQ2 [Direct mapping] Ubiquitin carboxyl-terminal hydrolase 34 Show all	Enzymes ENZYME proteins Hydrolases Peptidases Cysteine-type peptidases THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004197 [cysteine-type endopeptidase activity] GO:0004843 [ubiquitin-specific protease activity] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006511 [ubiquitin-dependent protein catabolic process] GO:0016055 [Wnt signaling pathway] GO:0016579 [protein deubiquitination] GO:0036459 [ubiquitinyl hydrolase activity] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0061136 [regulation of proteasomal protein catabolic process] GO:0071108 [protein K48-linked deubiquitination] GO:0090263 [positive regulation of canonical Wnt signaling pathway] Show all	3546 aa 404.2 kDa	No	0
USP34-002 ENSP00000398960 ENST00000411912	H7C183 [Direct mapping] Ubiquitin carboxyl-terminal hydrolase 34 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0061136 [regulation of proteasomal protein catabolic process] Show all	1223 aa 140.1 kDa	No	0
USP34-005 ENSP00000398489 ENST00000436269	H7C150 [Direct mapping] Ubiquitin carboxyl-terminal hydrolase 34 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0061136 [regulation of proteasomal protein catabolic process] Show all	424 aa 47.5 kDa	No	0
USP34-006 ENSP00000410559 ENST00000453734	A0A0C4DG73 [Direct mapping] Ubiquitin carboxyl-terminal hydrolase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006511 [ubiquitin-dependent protein catabolic process] GO:0008234 [cysteine-type peptidase activity] GO:0016579 [protein deubiquitination] GO:0036459 [ubiquitinyl hydrolase activity] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0061136 [regulation of proteasomal protein catabolic process] Show all	810 aa 94.3 kDa	No	0