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Cancer tissues showed moderate to strong cytoplasmic positivity. Renal cancers were mainly negative.
GENE INFORMATION
Gene name
IL1RL2 (HGNC Symbol)
Synonyms
IL1R-rp2, IL1RRP2
Description
Interleukin 1 receptor-like 2 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq, Jul 2008]