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STRN

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GENERAL INFORMATION

Gene name

 STRN

Gene description

 Striatin, calmodulin binding protein

Protein class

 Cancer-related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the cytosol. In addition localized to the nucleoplasm.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Cytosol (approved)

Additional location

 In addition localized to the Nucleoplasm (approved)

Single-cell variation

 Single-cell variation in protein expression observed.

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA017286
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the cytosol. In addition localized to the nucleoplasm.

Main location

 Cytosol (approved)

Additional location

 Nucleoplasm (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA017286 A-431 Cytosol Intensity
HPA017286 U-2 OS Nucleoplasm
Actin filaments
Cytosol
HPA017286 U-251 MG Cytosol

GENE INFORMATION

Gene name

 STRN (HGNC Symbol)

Synonyms

 SG2NA

Description

 Striatin, calmodulin binding protein (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 p22.2

Chromosome location (bp)

 36843640 - 36966472

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000115808 (version 83.38)

Entrez gene

 6801

UniProt

 O43815 (UniProt - Evidence at protein level)

neXtProt

 NX_O43815

Antibodypedia

 STRN antibodies

PROTEIN BROWSER
STRN-001
STRN-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
STRN-001
ENSP00000263918
ENST00000263918
O43815 [Direct mapping]
Striatin
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000159 [protein phosphatase type 2A complex]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005737 [cytoplasm]
GO:0005923 [bicellular tight junction]
GO:0007626 [locomotory behavior]
GO:0008285 [negative regulation of cell proliferation]
GO:0014069 [postsynaptic density]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016358 [dendrite development]
GO:0030331 [estrogen receptor binding]
GO:0032403 [protein complex binding]
GO:0043025 [neuronal cell body]
GO:0043197 [dendritic spine]
GO:0045211 [postsynaptic membrane]
GO:0051721 [protein phosphatase 2A binding]
GO:0070016 [armadillo repeat domain binding]
GO:0070830 [bicellular tight junction assembly]
Show all
 780 aa
86.1 kDa 		No 0
STRN-201
ENSP00000368513
ENST00000379213
O43815 [Direct mapping]
Striatin
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000159 [protein phosphatase type 2A complex]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005737 [cytoplasm]
GO:0005923 [bicellular tight junction]
GO:0007626 [locomotory behavior]
GO:0008285 [negative regulation of cell proliferation]
GO:0014069 [postsynaptic density]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016358 [dendrite development]
GO:0030331 [estrogen receptor binding]
GO:0032403 [protein complex binding]
GO:0043025 [neuronal cell body]
GO:0043197 [dendritic spine]
GO:0045211 [postsynaptic membrane]
GO:0051721 [protein phosphatase 2A binding]
GO:0070016 [armadillo repeat domain binding]
GO:0070830 [bicellular tight junction assembly]
Show all
 731 aa
80.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.