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STRN

GENERAL INFORMATION

Gene name

 STRN

Gene description

 Striatin, calmodulin binding protein

Protein class

 Cancer-related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA017286
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 STRN (HGNC Symbol)

Synonyms

 SG2NA

Description

 Striatin, calmodulin binding protein (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 p22.2

Chromosome location (bp)

 36843640 - 36966472

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000115808 (version 83.38)

Entrez gene

 6801

UniProt

 O43815 (UniProt - Evidence at protein level)

neXtProt

 NX_O43815

Antibodypedia

 STRN antibodies

PROTEIN BROWSER
STRN-001
STRN-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
STRN-001
ENSP00000263918
ENST00000263918
O43815 [Direct mapping]
Striatin
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Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000159 [protein phosphatase type 2A complex]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005737 [cytoplasm]
GO:0005923 [bicellular tight junction]
GO:0007626 [locomotory behavior]
GO:0008285 [negative regulation of cell proliferation]
GO:0014069 [postsynaptic density]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016358 [dendrite development]
GO:0030331 [estrogen receptor binding]
GO:0032403 [protein complex binding]
GO:0043025 [neuronal cell body]
GO:0043197 [dendritic spine]
GO:0045211 [postsynaptic membrane]
GO:0051721 [protein phosphatase 2A binding]
GO:0070016 [armadillo repeat domain binding]
GO:0070830 [bicellular tight junction assembly]
Show all
 780 aa
86.1 kDa 		No 0
STRN-201
ENSP00000368513
ENST00000379213
O43815 [Direct mapping]
Striatin
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000159 [protein phosphatase type 2A complex]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005737 [cytoplasm]
GO:0005923 [bicellular tight junction]
GO:0007626 [locomotory behavior]
GO:0008285 [negative regulation of cell proliferation]
GO:0014069 [postsynaptic density]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016358 [dendrite development]
GO:0030331 [estrogen receptor binding]
GO:0032403 [protein complex binding]
GO:0043025 [neuronal cell body]
GO:0043197 [dendritic spine]
GO:0045211 [postsynaptic membrane]
GO:0051721 [protein phosphatase 2A binding]
GO:0070016 [armadillo repeat domain binding]
GO:0070830 [bicellular tight junction assembly]
Show all
 731 aa
80.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.