Tissue expression of DCAF17 - Summary - The Human Protein Atlas

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DCAF17

TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	DCAF17
Gene description	DDB1 and CUL4 associated factor 17
Protein class	Disease related genes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA053339 , HPA055040
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	DCAF17 (HGNC Symbol)
Synonyms	C2orf37, FLJ13096
Description	DDB1 and CUL4 associated factor 17 (HGNC Symbol)
Entrez gene summary	This gene encodes a nuclear transmembrane protein that associates with cullin 4A/damaged DNA binding protein 1 ubiquitin ligase complex. Mutations in this gene are associated with Woodhouse-Sakati syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Chromosome	2
Cytoband	q31.1
Chromosome location (bp)	171434217 - 171485052
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000115827 (version 83.38)
Entrez gene	80067
UniProt	Q5H9S7 (UniProt - Evidence at protein level)
neXtProt	NX_Q5H9S7
Antibodypedia	DCAF17 antibodies

PROTEIN BROWSER

DCAF17-001	DCAF17-003	DCAF17-008	DCAF17-201	DCAF17-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DCAF17-001 ENSP00000364404 ENST00000375255	Q5H9S7 [Direct mapping] DDB1- and CUL4-associated factor 17 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Protein evidence (Kim et al 2014) Show all	GO:0005730 [nucleolus] GO:0016021 [integral component of membrane] GO:0016567 [protein ubiquitination] GO:0080008 [Cul4-RING E3 ubiquitin ligase complex] Show all	520 aa 58.8 kDa	No	1
DCAF17-003 ENSP00000342160 ENST00000339506	H0Y2X0 [Direct mapping] DDB1- and CUL4-associated factor 17 Show all	Predicted intracellular proteins Show all		271 aa 30.9 kDa	No	0
DCAF17-008 ENSP00000403992 ENST00000431110	H7C244 [Direct mapping] DDB1- and CUL4-associated factor 17 Show all	Predicted intracellular proteins Show all		222 aa 25.3 kDa	No	0
DCAF17-201 ENSP00000442238 ENST00000539783	F5H7W1 [Direct mapping] DDB1- and CUL4-associated factor 17 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all		453 aa 51.1 kDa	No	1
DCAF17-202 ENSP00000477604 ENST00000611110	Q5H9S7 [Direct mapping] DDB1- and CUL4-associated factor 17 Show all	Predicted intracellular proteins Disease related genes Show all	GO:0005730 [nucleolus] GO:0016021 [integral component of membrane] GO:0016567 [protein ubiquitination] GO:0080008 [Cul4-RING E3 ubiquitin ligase complex] Show all	240 aa 27.5 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.