Cell atlas - RND3 - The Human Protein Atlas

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RND3

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	RND3
Gene description	Rho family GTPase 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (BJ hTERT+, BJ)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (BJ hTERT+, BJ) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	RND3 (HGNC Symbol)
Synonyms	ARHE, Rho8, RhoE
Description	Rho family GTPase 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
Chromosome	2
Cytoband	q23.3
Chromosome location (bp)	150468195 - 150539011
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000115963 (version 83.38)
Entrez gene	390
UniProt	P61587 (UniProt - Evidence at protein level)
neXtProt	NX_P61587
Antibodypedia	RND3 antibodies

PROTEIN BROWSER

RND3-001	RND3-002	RND3-003	RND3-004	RND3-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RND3-001 ENSP00000263895 ENST00000263895	P61587 [Direct mapping] Rho-related GTP-binding protein RhoE Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005925 [focal adhesion] GO:0007155 [cell adhesion] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0030036 [actin cytoskeleton organization] GO:0070062 [extracellular exosome] Show all	244 aa 27.4 kDa	No	0
RND3-002 ENSP00000364886 ENST00000375734	P61587 [Direct mapping] Rho-related GTP-binding protein RhoE Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005925 [focal adhesion] GO:0007155 [cell adhesion] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0030036 [actin cytoskeleton organization] GO:0070062 [extracellular exosome] Show all	244 aa 27.4 kDa	No	0
RND3-003 ENSP00000395997 ENST00000439275	Q53RZ3 [Direct mapping] Putative uncharacterized protein ARHE; Rho-related GTP-binding protein RhoE Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0007264 [small GTPase mediated signal transduction] Show all	116 aa 13.1 kDa	No	0
RND3-004 ENSP00000411950 ENST00000454202	Q53RZ3 [Direct mapping] Putative uncharacterized protein ARHE; Rho-related GTP-binding protein RhoE Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0007264 [small GTPase mediated signal transduction] Show all	116 aa 13.1 kDa	No	0
RND3-007 ENSP00000386576 ENST00000409557	E9PFH1 [Direct mapping] Rho-related GTP-binding protein RhoE Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0007264 [small GTPase mediated signal transduction] Show all	115 aa 12.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.