Cell atlas - PCYOX1 - The Human Protein Atlas

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PCYOX1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	PCYOX1
Gene description	Prenylcysteine oxidase 1
Protein class	Enzymes Plasma proteins Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	PCYOX1 (HGNC Symbol)
Synonyms	KIAA0908, PCL1
Description	Prenylcysteine oxidase 1 (HGNC Symbol)
Entrez gene summary	Prenylcysteine is released during the degradation of prenylated proteins. PCYOX1 catalyzes the degradation of prenylcysteine to yield free cysteines and a hydrophobic isoprenoid product (Tschantz et al., 1999 [PubMed 10585463]).[supplied by OMIM, Mar 2008]
Chromosome	2
Cytoband	p13.3
Chromosome location (bp)	70257386 - 70281191
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000116005 (version 83.38)
Entrez gene	51449
UniProt	Q9UHG3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UHG3
Antibodypedia	PCYOX1 antibodies

PROTEIN BROWSER

PCYOX1-001	PCYOX1-002	PCYOX1-003	PCYOX1-004	PCYOX1-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PCYOX1-001 ENSP00000387654 ENST00000433351	Q9UHG3 [Direct mapping] Prenylcysteine oxidase 1 Show all	Enzymes ENZYME proteins Oxidoreductases MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001735 [prenylcysteine oxidase activity] GO:0005764 [lysosome] GO:0005774 [vacuolar membrane] GO:0005886 [plasma membrane] GO:0006821 [chloride transport] GO:0008555 [chloride-transporting ATPase activity] GO:0016670 [oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor] GO:0030327 [prenylated protein catabolic process] GO:0030328 [prenylcysteine catabolic process] GO:0030329 [prenylcysteine metabolic process] GO:0034361 [very-low-density lipoprotein particle] GO:0055114 [oxidation-reduction process] GO:0070062 [extracellular exosome] GO:1902476 [chloride transmembrane transport] Show all	505 aa 56.6 kDa	Yes	0
PCYOX1-002 ENSP00000264441 ENST00000264441	F8W8W4 [Direct mapping] Prenylcysteine oxidase 1 Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001735 [prenylcysteine oxidase activity] GO:0005774 [vacuolar membrane] GO:0016670 [oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor] GO:0030328 [prenylcysteine catabolic process] GO:0055114 [oxidation-reduction process] Show all	293 aa 32.3 kDa	Yes	0
PCYOX1-003 ENSP00000404327 ENST00000422380	C9JGT6 [Direct mapping] Prenylcysteine oxidase 1 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001735 [prenylcysteine oxidase activity] GO:0005774 [vacuolar membrane] GO:0016670 [oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor] GO:0030328 [prenylcysteine catabolic process] GO:0055114 [oxidation-reduction process] Show all	130 aa 14.9 kDa	No	0
PCYOX1-004 ENSP00000408751 ENST00000451279	C9JM55 [Direct mapping] Prenylcysteine oxidase 1 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001735 [prenylcysteine oxidase activity] GO:0005774 [vacuolar membrane] GO:0016670 [oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor] GO:0030328 [prenylcysteine catabolic process] GO:0055114 [oxidation-reduction process] Show all	154 aa 17.7 kDa	No	0
PCYOX1-006 ENSP00000413178 ENST00000414812	C9K055 [Direct mapping] Prenylcysteine oxidase 1 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001735 [prenylcysteine oxidase activity] GO:0005774 [vacuolar membrane] GO:0016670 [oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor] GO:0030328 [prenylcysteine catabolic process] GO:0055114 [oxidation-reduction process] Show all	209 aa 23.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.